{"id":"W1978636681","doi":"10.1016/j.ymeth.2012.07.012","title":"Uniform amplification of phage display libraries in monodisperse emulsions","year":2012,"lang":"en","type":"article","venue":"Methods","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Alberta Glycomics Centre","funders":"Alberta Glycomics Centre","keywords":"Microfluidics; Phage display; Dispersity; clone (Java method); Escherichia coli; Bacterial virus; Phagemid; Nanotechnology; Chemistry; Biophysics; Biology; Bacteriophage; Materials science; DNA; Biochemistry; Genetics; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001473631,0.0006911541,0.000512429,0.0008319411,0.0003309472,0.0009423018,0.0005703959,0.0003873155,0.001979823],"category_scores_gemma":[0.001118731,0.0005811717,0.0004071234,0.0006338397,0.0003717233,0.0005500006,0.0009953603,0.001050213,0.001081786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005278561,"about_ca_system_score_gemma":0.0002861859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002172205,"about_ca_topic_score_gemma":0.0005054544,"domain_scores_codex":[0.9992734,0.0001253508,0.00005330799,0.0001833505,0.0002273462,0.0001372294],"domain_scores_gemma":[0.9995448,0.0002166716,0.00004783105,0.00005595981,0.00008102823,0.00005377288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000552742,0.0000183594,0.00005623584,0.00004894035,0.00000597955,0.00002262889,0.0000381768,0.0001532222,0.99523,0.000497292,0.00008854746,0.003785418],"study_design_scores_gemma":[0.00001240129,0.00004896656,0.0001268372,0.000004743175,0.000006599531,0.00003686547,0.000008582682,0.001005644,0.9973207,0.0001642376,0.001260827,0.000003621014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.425405,0.00189893,0.5626276,0.000271507,0.0001281471,0.0005207065,0.0005839822,0.001389652,0.007174555],"genre_scores_gemma":[0.7861768,0.002460194,0.1916334,0.000345118,0.0000556188,0.0008520542,0.001739466,0.000596311,0.01614112],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001979823,"threshold_uncertainty_score":0.007793427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08222752425119824,"score_gpt":0.4504849282572534,"score_spread":0.3682574040060552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}