{"id":"W1978657122","doi":"10.1002/biof.179","title":"Schisandrin B enhances the glutathione redox cycling and protects against oxidant injury in different types of cultured cells","year":2011,"lang":"en","type":"article","venue":"BioFactors","topic":"Plant-derived Lignans Synthesis and Bioactivity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"Glutathione; Cytoprotection; Chemistry; Glutathione reductase; Oxidative stress; Redox; Biochemistry; Cysteine; Buthionine sulfoximine; Pharmacology; Biology; Enzyme; Glutathione peroxidase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001148086,0.0001396158,0.0001751045,0.00003781065,0.00004567445,0.000009223447,0.0001203127,0.0001219139,0.000005739931],"category_scores_gemma":[0.00003250912,0.00007814926,0.00005032678,0.00005567362,0.00010788,0.000004398749,0.00006784726,0.00007952142,8.207606e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006447284,"about_ca_system_score_gemma":0.00001797592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007763646,"about_ca_topic_score_gemma":0.00006866664,"domain_scores_codex":[0.9993076,0.00007090125,0.0001693312,0.0002192015,0.00007818396,0.0001548134],"domain_scores_gemma":[0.9996611,0.00001405075,0.000104726,0.0001651422,0.00001652614,0.00003846013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009619971,0.00008764271,0.002598503,0.00001646086,0.00003560851,9.864957e-7,0.0002626559,5.117903e-7,0.995082,0.000007973686,0.00001579683,0.001795637],"study_design_scores_gemma":[0.0001087639,0.000110118,0.03550669,0.00004203172,0.0000100085,8.148967e-7,0.0001072926,0.000009479702,0.9635522,0.000009935289,0.0004298805,0.0001128049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992477,0.0001951083,0.00002415517,0.00002004111,0.00008419262,0.0002023659,0.00004456467,0.000005892106,0.0001759764],"genre_scores_gemma":[0.9992795,0.0004721952,0.0001383781,0.00002161004,0.00003667807,0.00001246928,0.000009241912,0.000008075829,0.00002187129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03290819,"threshold_uncertainty_score":0.3186834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0134823915885515,"score_gpt":0.2123602154155827,"score_spread":0.1988778238270312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}