{"id":"W1978683702","doi":"10.1002/syn.20211","title":"Increased expression of calcium/calmodulin-dependent protein kinase IIβ in frontal cortex in schizophrenia and depression","year":2005,"lang":"en","type":"article","venue":"Synapse","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Schizophrenia (object-oriented programming); Synaptic pruning; Calmodulin; Depression (economics); Gene expression; splice; Neuroscience; Cerebral cortex; Cortex (anatomy); Kinase; Prefrontal cortex; Frontal lobe; Protein kinase A; Internal medicine; Biology; Endocrinology; Gene; Calcium; Medicine; Cell biology; Psychiatry; Biochemistry; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002873851,0.0001581113,0.0002306117,0.0003723286,0.0000681858,0.00001807139,0.0003137381,0.00009302534,0.0001637243],"category_scores_gemma":[0.000591171,0.0001362576,0.00002822802,0.000368172,0.0002743485,0.0002571788,0.000290771,0.0003935991,0.00003522457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000037362,"about_ca_system_score_gemma":0.00006939508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001057091,"about_ca_topic_score_gemma":0.00006767151,"domain_scores_codex":[0.9978579,0.0004237572,0.000316159,0.0006410783,0.000367346,0.0003937453],"domain_scores_gemma":[0.99935,0.0001412783,0.00008997953,0.0002462834,0.00001434497,0.0001581184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006607081,0.0003630497,0.008331938,0.00001752661,2.721564e-7,0.0004091957,0.00006914524,0.00001766397,0.9882624,0.00002027875,0.00002745528,0.00182034],"study_design_scores_gemma":[0.002336571,0.0001131524,0.03224365,0.0000764955,0.000001570938,0.00002789026,0.00001689907,0.001252338,0.9637328,0.00004165862,0.00003622344,0.0001207688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986452,0.00007533545,0.000009205894,0.0000962003,0.00005780075,0.0006419063,0.00001010861,0.00002985529,0.0004343816],"genre_scores_gemma":[0.9992752,0.00003570429,0.00007249224,0.0001460071,0.00003182097,0.00006886604,3.689277e-7,0.00002338633,0.0003461377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02452964,"threshold_uncertainty_score":0.5556424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02774383876824139,"score_gpt":0.3139940995005374,"score_spread":0.286250260732296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}