{"id":"W1978690745","doi":"10.1038/jcbfm.2015.47","title":"Intraventricular Fibrinolysis with Tissue Plasminogen Activator is Associated with Transient Cerebrospinal Fluid Inflammation: A Randomized Controlled Trial","year":2015,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Alberta; University of Calgary","funders":"","keywords":"Fibrinolysis; Cerebrospinal fluid; Tissue plasminogen activator; Medicine; Inflammation; Randomized controlled trial; Plasminogen activator; T-plasminogen activator; Cardiology; Anesthesia; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002914232,0.0006101972,0.004571449,0.0006306751,0.0001713359,0.000173863,0.0003357228,0.0003365568,0.0006315935],"category_scores_gemma":[0.001383675,0.0003325655,0.001005962,0.0008747879,0.0002764185,0.0005986083,0.00004183749,0.001062597,0.00002422852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001563207,"about_ca_system_score_gemma":0.001481339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000239555,"about_ca_topic_score_gemma":0.000006724475,"domain_scores_codex":[0.99312,0.0008030446,0.001911075,0.0004233267,0.002944294,0.0007983142],"domain_scores_gemma":[0.9946541,0.0003606499,0.001281816,0.0004044269,0.00230402,0.0009950293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9798983,0.001148599,0.0001421642,0.00007235797,0.007164924,0.001443082,0.001408741,0.0002099625,0.003887773,0.0001128826,0.0005020514,0.004009107],"study_design_scores_gemma":[0.9160523,0.004020362,0.0001954416,0.0002745436,0.008591439,0.002155818,0.0002356771,0.005310048,0.06214904,0.00007770345,0.0005335839,0.0004039885],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877931,0.00209121,0.001737068,0.003206891,0.000405693,0.004036845,0.00001999907,0.00004944166,0.0006597779],"genre_scores_gemma":[0.9868311,0.0001158129,0.008668901,0.0002341365,0.002559349,0.000166825,0.00002959161,0.00008518974,0.001309143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06384601,"threshold_uncertainty_score":0.9999126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01296167736578635,"score_gpt":0.2515576938503418,"score_spread":0.2385960164845555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}