{"id":"W1978699635","doi":"10.1016/j.jchromb.2011.07.031","title":"Simultaneous quantification of VX and its toxic metabolite in blood and plasma samples and its application for in vivo and in vitro toxicological studies","year":2011,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Pesticide Exposure and Toxicity","field":"Agricultural and Biological Sciences","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Defence Research and Development Canada","funders":"Ministère de la Défense Nationale","keywords":"Chemistry; Metabolite; In vivo; Toxicokinetics; Nerve agent; Chromatography; Detection limit; Pharmacology; Quantitative analysis (chemistry); Whole blood; Toxicity; Enzyme; Biochemistry; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009726788,0.0008947231,0.0006128542,0.0006573147,0.0006119623,0.0007098493,0.0003647425,0.001147941,0.001505184],"category_scores_gemma":[0.00117972,0.0004896398,0.0004638742,0.0005472495,0.0007473429,0.0007436423,0.0003572556,0.000985973,0.0005561363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003062615,"about_ca_system_score_gemma":0.001043825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009857477,"about_ca_topic_score_gemma":0.001581704,"domain_scores_codex":[0.9993693,0.0001997245,0.00004746063,0.000182485,0.0001471922,0.00005386325],"domain_scores_gemma":[0.9995572,0.0001680751,0.00007431889,0.00005289847,0.00009971843,0.00004776118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000771437,0.000085936,0.001369567,0.0001298219,0.00005214137,0.0001768301,0.0001180651,0.0001487626,0.9856533,0.0002861345,0.0001455123,0.01106259],"study_design_scores_gemma":[0.00002980313,0.0007734185,0.00370693,0.00001382679,0.00008646359,0.0008435003,0.00006439127,0.001337626,0.9904399,0.0002192478,0.002469551,0.00001542651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7151434,0.02109156,0.2532478,0.0008608832,0.0004969469,0.0008741616,0.001504634,0.0008394265,0.005941229],"genre_scores_gemma":[0.8593732,0.008885468,0.1185127,0.0004325947,0.0002146998,0.001361062,0.001351757,0.00008242281,0.009786076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001505184,"threshold_uncertainty_score":0.00514406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05204188114079575,"score_gpt":0.2648613464231936,"score_spread":0.2128194652823979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}