{"id":"W1978793943","doi":"10.1021/bp049756i","title":"Asymmetrical Synthesis of l-Homophenylalanine Using Engineered Escherichia coli Aspartate Aminotransferase","year":2005,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Public Health Agency of Canada","keywords":"Escherichia coli; Chemistry; Biochemistry; Microbiology; Biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001929961,0.0004631648,0.0003631673,0.0001841422,0.0001356362,0.000315982,0.0002950232,0.000327181,0.0006985678],"category_scores_gemma":[0.0002028618,0.0001886546,0.0001925643,0.0002470232,0.0001805675,0.0002339975,0.0002883559,0.0004939071,0.0006506568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003341642,"about_ca_system_score_gemma":0.000405382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006040116,"about_ca_topic_score_gemma":0.0008601418,"domain_scores_codex":[0.9997998,0.00003881936,0.00002260507,0.00004499012,0.00005159225,0.00004222036],"domain_scores_gemma":[0.99983,0.00002392889,0.00004094475,0.00003651383,0.00003040626,0.00003808965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000047881,0.00001893737,0.00008031692,0.00002596333,0.000003689093,0.00007370528,0.000007989754,0.0001117802,0.9975464,0.0001632954,0.00002394643,0.001896039],"study_design_scores_gemma":[0.000009285682,0.00007943143,0.0003234366,0.000001716578,0.000005868124,0.0001616658,0.000006535393,0.000656603,0.9971842,0.00003259582,0.001534798,0.000003929159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.949244,0.0006252111,0.04467794,0.0001588305,0.0000973503,0.0001245574,0.0006728025,0.0003310701,0.004068319],"genre_scores_gemma":[0.9668468,0.0005920185,0.02763556,0.00004792093,0.00001017584,0.0000384439,0.0007107469,0.00007935955,0.004039014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006985678,"threshold_uncertainty_score":0.002424479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006612054862221,"score_gpt":0.2420116323477923,"score_spread":0.2319455117991701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}