{"id":"W1978815390","doi":"10.1160/th03-01-0045","title":"Affinity and kinetics of P-selectin binding to heparin","year":2003,"lang":"en","type":"article","venue":"Thrombosis and Haemostasis","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Chinese Academy of Sciences","keywords":"P-selectin; Heparin; Selectin; Chemistry; Surface plasmon resonance; Biophysics; Platelet; L-selectin; Endothelium; Adhesion; Receptor–ligand kinetics; Platelet membrane glycoprotein; Kinetics; Dissociation constant; Molecular biology; Glycoprotein; Biochemistry; Platelet activation; Immunology; Biology; Endocrinology; Receptor; Materials science; Nanotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000237091,0.0003523892,0.0002973653,0.000323034,0.0001996023,0.0005384042,0.0002689471,0.0002486925,0.001890143],"category_scores_gemma":[0.0009924652,0.0002519526,0.0001733553,0.000272389,0.0001933962,0.0002752634,0.0001781676,0.000410714,0.0008708684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005204277,"about_ca_system_score_gemma":0.0002365358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003530121,"about_ca_topic_score_gemma":0.001476889,"domain_scores_codex":[0.9996325,0.00005137869,0.00001193483,0.00007886662,0.00009994626,0.0001253466],"domain_scores_gemma":[0.9995159,0.0002343623,0.00006444207,0.00002972237,0.00009527718,0.00006020758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004445091,0.00006950399,0.003340662,0.00006014157,0.00002207201,0.00008402255,0.000103554,0.0006057963,0.9878633,0.0003376889,0.0002362037,0.006832585],"study_design_scores_gemma":[0.00003120308,0.000444933,0.05370412,0.00001740266,0.00003275588,0.0004647803,0.000117112,0.01707037,0.9251696,0.0002908129,0.002624805,0.00003209131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918836,0.001222576,0.004172579,0.00005138762,0.00001123126,0.00003408455,0.0002726238,0.00005237836,0.00229953],"genre_scores_gemma":[0.9934603,0.0007350126,0.001072232,0.00005121859,0.000007472997,0.00003643422,0.0005387703,0.00002575703,0.004072851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003530121,"threshold_uncertainty_score":0.007019162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08712107063651532,"score_gpt":0.3609302963769561,"score_spread":0.2738092257404408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}