{"id":"W1978831695","doi":"10.1128/iai.00193-11","title":"The Stringent Response Is Essential for Pseudomonas aeruginosa Virulence in the Rat Lung Agar Bead and Drosophila melanogaster Feeding Models of Infection","year":2011,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"University of British Columbia; University of Washington","keywords":"Biology; Virulence; Pseudomonas aeruginosa; Mutant; Microbiology; Drosophila melanogaster; Pyocyanin; Bacteria; Genetics; Quorum sensing; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000171361,0.0007483299,0.0003226311,0.0004684716,0.0003199287,0.0002682101,0.0003405285,0.0005489837,0.001468471],"category_scores_gemma":[0.000165621,0.0002554003,0.0004997615,0.0001777226,0.0002954846,0.0002328544,0.0004062713,0.0008668008,0.0003858029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004223148,"about_ca_system_score_gemma":0.0003728349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002831619,"about_ca_topic_score_gemma":0.004641372,"domain_scores_codex":[0.999642,0.00007280231,0.00005408521,0.00005904579,0.0001111071,0.00006099369],"domain_scores_gemma":[0.9996803,0.00004388262,0.000112952,0.00004041901,0.00003200033,0.000090375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007945028,0.0000309123,0.0002168152,0.00002302759,0.000003322105,0.00006160587,0.00001715376,0.00002519041,0.9992052,0.00004825982,0.00002147668,0.000267535],"study_design_scores_gemma":[0.0000460489,0.00102101,0.0229453,0.00001743761,0.00002582767,0.0007009793,0.0001023327,0.001264529,0.9720342,0.00007072102,0.001745709,0.00002604103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948952,0.0006293203,0.00198876,0.0001215103,0.00001956301,0.00007102123,0.0008874526,0.00006545147,0.001321845],"genre_scores_gemma":[0.9866151,0.0007489918,0.005573817,0.0001110141,0.000008558124,0.000177318,0.001205531,0.00004293348,0.005516726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002831619,"threshold_uncertainty_score":0.005630314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03230756870816601,"score_gpt":0.289173394134691,"score_spread":0.2568658254265249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}