{"id":"W1978835419","doi":"10.1111/imm.12433","title":"The atypical <scp>MAPK ERK</scp>3 controls positive selection of thymocytes","year":2014,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"MAPK/ERK pathway; Thymocyte; Biology; Kinase; T-cell receptor; Cell biology; Molecular biology; Transgene; T cell; Immunology; Gene; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001098006,0.0003887316,0.0001891299,0.0003509287,0.0002550755,0.0004209767,0.0002598347,0.0002704854,0.002644315],"category_scores_gemma":[0.0001619042,0.0001462716,0.0002332708,0.0001871009,0.0003728102,0.0002374939,0.0003283773,0.0005227151,0.0009498594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000338686,"about_ca_system_score_gemma":0.0002462948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004324865,"about_ca_topic_score_gemma":0.000961828,"domain_scores_codex":[0.9997748,0.00002468412,0.00001772827,0.00004747006,0.00006765251,0.00006760596],"domain_scores_gemma":[0.999737,0.00002461337,0.00010531,0.0000234229,0.00002554265,0.00008408093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008717104,0.00001022712,0.0001866591,0.00001446208,0.000001634363,0.00005511751,0.000006008265,0.00002328032,0.9987979,0.0001111916,0.00004239283,0.0006639913],"study_design_scores_gemma":[0.0000196406,0.00007286909,0.01406988,0.000008322429,0.000008870273,0.0006685887,0.00003422227,0.001319752,0.9806348,0.0001592125,0.002995935,0.000007968242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928861,0.0006446873,0.003199949,0.00009083288,0.00003187011,0.0000178429,0.0005479031,0.0001933605,0.002387291],"genre_scores_gemma":[0.9942985,0.0003618407,0.001511999,0.00003990941,0.00001141879,0.00002184313,0.0004973894,0.00008551065,0.003171616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002644315,"threshold_uncertainty_score":0.008846045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005399657994620599,"score_gpt":0.2084071306110851,"score_spread":0.2030074726164645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}