{"id":"W1978835419","doi":"10.1111/imm.12433","title":"The atypical <scp>MAPK ERK</scp>3 controls positive selection of thymocytes","year":2014,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"MAPK/ERK pathway; Thymocyte; Biology; Kinase; T-cell receptor; Cell biology; Molecular biology; Transgene; T cell; Immunology; Gene; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000546768,0.0003405662,0.0006600274,0.0001521458,0.000640517,0.00002276624,0.0006591894,0.0008009548,0.0001695651],"category_scores_gemma":[0.0008069114,0.000244405,0.0002330753,0.0002392411,0.001629091,0.00009211934,0.0002209751,0.0008443408,0.00118467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005930007,"about_ca_system_score_gemma":0.00009022556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000148736,"about_ca_topic_score_gemma":0.00007479352,"domain_scores_codex":[0.9968551,0.001108738,0.0006504772,0.0004562246,0.00005254843,0.0008768942],"domain_scores_gemma":[0.9957817,0.00300513,0.0003867401,0.0005376855,0.000265594,0.00002319634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004261114,0.0001888075,0.001462467,0.000005584447,0.000759448,0.000001656488,0.0002561303,0.000002896354,0.958175,0.02736351,0.002549382,0.008809024],"study_design_scores_gemma":[0.002723362,0.001385916,0.01761142,0.00001926723,0.00009913441,0.0002652146,0.0003516638,0.00001660607,0.7847223,0.002083762,0.1905976,0.0001237042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977144,0.01203543,0.0006878098,0.0006713367,0.002450261,0.0004224335,0.00002073888,0.0001740553,0.006393949],"genre_scores_gemma":[0.9923196,0.000483474,0.00005900608,0.0002311111,0.00009854457,0.00006064594,0.00006877993,0.00003267597,0.006646187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1880483,"threshold_uncertainty_score":0.999593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005399657994620599,"score_gpt":0.2084071306110851,"score_spread":0.2030074726164645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}