{"id":"W1978882188","doi":"10.1158/0008-5472.sabcs-09-47","title":"CIRG/TORI 010: 10-Month Analysis of a Randomized Phase II Trial of Motesanib Plus Weekly Paclitaxel as First Line Therapy in HER2-Negative Metastatic Breast Cancer (MBC).","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Saint-Sacrement","funders":"","keywords":"Medicine; Metastatic breast cancer; Internal medicine; Placebo; Breast cancer; Gastroenterology; Surgery; Urology; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002975864,0.0004337605,0.003235342,0.001629873,0.0001597026,0.00002323349,0.0004313396,0.0001535307,0.003783912],"category_scores_gemma":[0.001019352,0.0003377895,0.0007442036,0.004686898,0.000948242,0.0002309007,0.00008043589,0.0007269757,0.000004903433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001276078,"about_ca_system_score_gemma":0.001731195,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01751379,"about_ca_topic_score_gemma":0.002475323,"domain_scores_codex":[0.9942613,0.000908206,0.001393618,0.0007611898,0.001807004,0.0008686429],"domain_scores_gemma":[0.9953294,0.001267112,0.0005776515,0.0008671409,0.001637251,0.0003214258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.880442,0.002992902,0.00009156089,0.0001442994,0.005025958,0.00004993098,0.004941166,0.001639145,0.0108208,0.0001277322,0.0001624072,0.09356206],"study_design_scores_gemma":[0.9641602,0.00877448,0.001708893,0.0008443359,0.001528205,0.000007885701,0.00108313,0.002437889,0.01613283,0.001949452,0.0009785609,0.0003941599],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733323,0.01029663,0.0003693966,0.009751879,0.0001644819,0.004808777,0.0007460802,0.00004363995,0.0004867803],"genre_scores_gemma":[0.9884875,0.00746448,0.0003741863,0.0002092596,0.000411479,0.001281475,0.00005156684,0.00005975406,0.001660273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0931679,"threshold_uncertainty_score":0.9999074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07820365543155519,"score_gpt":0.4614026070120939,"score_spread":0.3831989515805387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}