{"id":"W1978882737","doi":"10.1021/ol051483k","title":"Total Synthesis and Structural Confirmation of (+)-Longicin","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Acetogenin; Butenolide; Stereocenter; Chemistry; Polyketide; Stereochemistry; Total synthesis; Natural product; Enantioselective synthesis; Biosynthesis; Organic chemistry; Catalysis; Botany; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003028964,0.0000552619,0.00006279902,0.00001577913,0.00002117418,0.000003608267,0.00003784413,0.00003041082,0.0000796398],"category_scores_gemma":[0.00002289725,0.00004793967,0.00002087581,0.00002005741,0.00005813306,0.000003917406,0.00001440367,0.00002663899,0.00000440029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005339693,"about_ca_system_score_gemma":0.00001119451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006636574,"about_ca_topic_score_gemma":0.000005156091,"domain_scores_codex":[0.9996769,0.00001008333,0.00008481327,0.00009314409,0.00006389866,0.00007112637],"domain_scores_gemma":[0.9998417,0.000009632331,0.00003354706,0.00006773167,0.00001485516,0.00003246658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001777517,0.000005042315,0.0003635152,0.000009227701,0.00001748887,6.335227e-7,0.00003420296,0.000008328424,0.9958275,0.00007382828,0.001666489,0.001975987],"study_design_scores_gemma":[0.000261659,0.0000635024,0.03630663,0.00001163745,0.0000194543,0.00007725626,0.00003959198,0.00002652535,0.9604273,0.0000101088,0.002670522,0.00008574852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954947,0.0001555437,0.0001379688,0.004030094,0.00003970922,0.00003648074,0.00001113938,0.000004224493,0.000090144],"genre_scores_gemma":[0.9983483,0.00002156869,0.0003284414,0.00102803,0.0002097099,0.000001454678,0.00002739246,0.000005692174,0.00002939737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03594312,"threshold_uncertainty_score":0.1954923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004639720302163067,"score_gpt":0.1984004787173828,"score_spread":0.1937607584152198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}