{"id":"W1978882737","doi":"10.1021/ol051483k","title":"Total Synthesis and Structural Confirmation of (+)-Longicin","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Acetogenin; Butenolide; Stereocenter; Chemistry; Polyketide; Stereochemistry; Total synthesis; Natural product; Enantioselective synthesis; Biosynthesis; Organic chemistry; Catalysis; Botany; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002526931,0.0004181363,0.000246066,0.0002098239,0.000354569,0.0003380141,0.0003009498,0.0001881417,0.001718468],"category_scores_gemma":[0.0002135845,0.000114612,0.0002046105,0.0003755444,0.0002533109,0.0003511258,0.0002692293,0.0005716234,0.0006744935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003942742,"about_ca_system_score_gemma":0.0004964307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008157697,"about_ca_topic_score_gemma":0.0008680071,"domain_scores_codex":[0.99984,0.00003228278,0.00001345,0.00003126974,0.00004157967,0.00004136725],"domain_scores_gemma":[0.999792,0.00002109187,0.00004515109,0.00004532309,0.00004792207,0.00004853035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001018393,0.00002156561,0.00004985083,0.00009481966,0.0000080174,0.0001743941,0.00004911669,0.0002989356,0.9904055,0.0008535601,0.0001277629,0.007814554],"study_design_scores_gemma":[0.00001742037,0.0003123685,0.0003770542,0.000006868992,0.00002024813,0.0002560706,0.00003641363,0.0002140867,0.9875247,0.000226901,0.01099861,0.000009196646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9082307,0.004644961,0.05508458,0.0003164884,0.0002460989,0.000246999,0.003130931,0.0004518815,0.02764744],"genre_scores_gemma":[0.9663535,0.002311989,0.02249731,0.00009485719,0.00003321212,0.00004283736,0.001888103,0.00008657536,0.006691774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001718468,"threshold_uncertainty_score":0.005748808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004639720302163067,"score_gpt":0.1984004787173828,"score_spread":0.1937607584152198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}