{"id":"W1978920270","doi":"10.1074/jbc.m703423200","title":"APOBEC3G Inhibits DNA Strand Transfer during HIV-1 Reverse Transcription","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"APOBEC3G; DNA; Transcription bubble; Chemistry; Reverse transcriptase; Human immunodeficiency virus (HIV); Cell biology; Virology; Molecular biology; Biophysics; Biology; Cytidine deaminase; Biochemistry; Polymerase chain reaction; Gene; Polymerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004619289,0.0001468528,0.0002764208,0.0000310163,0.00009869118,0.000009123642,0.000153049,0.0003368565,0.001365704],"category_scores_gemma":[0.00006455347,0.0000957235,0.0002263885,0.00008110139,0.0001716924,0.00006268408,0.0000120225,0.0005213153,0.0001268181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007296041,"about_ca_system_score_gemma":0.00003876254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002051814,"about_ca_topic_score_gemma":0.000001207566,"domain_scores_codex":[0.9989039,0.00005538136,0.000444073,0.0001551944,0.00006555298,0.0003759565],"domain_scores_gemma":[0.9995719,0.0000780756,0.00007238819,0.00009440725,0.00008843919,0.00009483213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001187742,0.0002500481,0.001794848,0.00003177242,0.0001389648,0.0001761575,0.00008726124,0.000001059896,0.9945651,0.000003856087,0.0005075264,0.00125567],"study_design_scores_gemma":[0.003066736,0.0002432361,0.01133846,0.00004459589,0.00002793192,0.0008067933,0.0001853687,4.359721e-8,0.9735355,0.0000227459,0.01062345,0.0001050791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967927,0.001434819,0.0002910541,0.00022559,0.00009278413,0.00007024026,0.00006640074,0.00001677206,0.001009658],"genre_scores_gemma":[0.9984065,0.0003180559,0.00004013184,0.00002977634,0.0001045233,0.000001283067,0.00008121599,0.000005946105,0.001012536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02102953,"threshold_uncertainty_score":0.9995472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02181333748792039,"score_gpt":0.2512585921900473,"score_spread":0.2294452547021269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}