{"id":"W1978942485","doi":"10.1038/ng2059","title":"Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice","year":2007,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Genome Canada","keywords":"Biology; Quantitative trait locus; Congenic; Allele; Locus (genetics); Gene; Genetics; Transferrin; Macrophage; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005487692,0.001545419,0.0007354267,0.002116462,0.0006618318,0.000715227,0.001202956,0.001991938,0.005655326],"category_scores_gemma":[0.0006061774,0.0007574041,0.001080846,0.0006550467,0.001573577,0.0002983308,0.000927529,0.00180588,0.0007933027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001174947,"about_ca_system_score_gemma":0.0005598753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0028325,"about_ca_topic_score_gemma":0.004497887,"domain_scores_codex":[0.9990857,0.0001940808,0.0001194217,0.0002806877,0.0001453749,0.0001747065],"domain_scores_gemma":[0.9984096,0.0003081415,0.0007578317,0.0001091974,0.0000513411,0.0003640068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001166063,0.00009946839,0.0004449049,0.00004235703,0.00005735417,0.0003993866,0.00004341931,0.0002315846,0.9959931,0.0004336909,0.0001053633,0.0009833145],"study_design_scores_gemma":[0.0008710611,0.001196648,0.03452366,0.0001220765,0.000675026,0.004122497,0.0003179153,0.007132719,0.9428362,0.001210536,0.006836653,0.0001549919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917086,0.0004633821,0.004251956,0.0004699724,0.000126188,0.00004525419,0.0014466,0.0003828483,0.001105277],"genre_scores_gemma":[0.9889739,0.0004179702,0.00455367,0.0003109426,0.00005225604,0.00009003333,0.0006196848,0.0005803966,0.004401234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005655326,"threshold_uncertainty_score":0.01891893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005838986547880901,"score_gpt":0.2487875777222672,"score_spread":0.2429485911743863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}