{"id":"W1979024723","doi":"10.1080/01635581.2011.605982","title":"Promoter Methylation of E-Cadherin, p16, and RAR-β<sub>2</sub>Genes in Breast Tumors and Dietary Intake of Nutrients Important in One-Carbon Metabolism","year":2011,"lang":"en","type":"article","venue":"Nutrition and Cancer","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; University of Guelph; U.S. Public Health Service; U.S. Department of Defense","keywords":"Methylation; DNA methylation; Odds ratio; Methionine; Breast cancer; Biology; Population; Carcinogenesis; Internal medicine; Endocrinology; Cancer; Medicine; Gene; Genetics; Gene expression; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001681213,0.00009831715,0.0001878406,0.00009322064,0.00001180621,0.00000421958,0.00002823914,0.0001074787,0.000003900434],"category_scores_gemma":[0.00000805112,0.00009142215,0.00002121015,0.0001008714,0.00007249111,0.000008920963,0.00003273245,0.00005089445,2.502631e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006144773,"about_ca_system_score_gemma":0.00001896252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002678696,"about_ca_topic_score_gemma":0.0002666071,"domain_scores_codex":[0.9992557,0.00004873702,0.0003033566,0.0002133578,0.00007824953,0.0001006171],"domain_scores_gemma":[0.9996826,0.000004760031,0.0001277719,0.00008584835,0.00005676104,0.0000422357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001843269,0.0001456569,0.1345886,0.0001319784,0.00001433874,6.726287e-7,0.0002104845,7.11697e-7,0.8453367,0.00002061622,0.00000100606,0.01936499],"study_design_scores_gemma":[0.0008983484,0.00007461081,0.3847849,0.00007775288,0.00001364251,0.00000136603,0.00005476485,0.00004844293,0.6133696,0.0005325489,0.00007021304,0.0000737499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737856,0.02582585,0.00001209085,0.00004127314,0.00003139626,0.0002243056,0.00003569193,0.000001879585,0.00004192628],"genre_scores_gemma":[0.9657688,0.0338752,0.000230079,0.00001494931,0.00002715606,0.00004015736,0.00003173616,0.000009249721,0.000002730844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2501964,"threshold_uncertainty_score":0.3728087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02144271781850644,"score_gpt":0.2446458117883217,"score_spread":0.2232030939698153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}