{"id":"W1979029561","doi":"10.7554/elife.03635","title":"Transcription mediated insulation and interference direct gene cluster expression switches","year":2014,"lang":"en","type":"article","venue":"eLife","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia; Engineering and Physical Sciences Research Council; National Institutes of Health; Deutsche Forschungsgemeinschaft; Natural Sciences and Engineering Research Council of Canada; European Commission; Wellcome Trust; Wellcome","keywords":"Promoter; Gene; Terminator (solar); Biology; Transcription (linguistics); RNA interference; Gene expression; Transcription factor; Genetics; Gene cluster; Regulation of gene expression; Cell biology; RNA; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000243811,0.00048166,0.0003407821,0.0001913417,0.0002165868,0.0006594813,0.0003823971,0.0003514595,0.001480429],"category_scores_gemma":[0.0004170288,0.0003439534,0.000422855,0.0001649184,0.0005293702,0.0004928316,0.0008512046,0.0008128951,0.000702059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005006292,"about_ca_system_score_gemma":0.0002412181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003190308,"about_ca_topic_score_gemma":0.0006073397,"domain_scores_codex":[0.9995849,0.00003234202,0.0000251865,0.0001849551,0.0000966494,0.00007608196],"domain_scores_gemma":[0.9996086,0.0001127904,0.0001006436,0.00007511322,0.00004141711,0.00006137799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004465767,0.000005051686,0.0003220711,0.00001950347,0.000002877651,0.00002742687,0.00001858855,0.0000664748,0.9975473,0.0004400795,0.00003117888,0.001474699],"study_design_scores_gemma":[0.000007913827,0.00004123763,0.002967458,0.00000392864,0.000009564278,0.0001552913,0.0000257457,0.001569225,0.9929059,0.0003884925,0.001918269,0.000006883401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9407791,0.001410044,0.04965511,0.0002076272,0.0001445082,0.00003378417,0.0004530571,0.0009819698,0.00633474],"genre_scores_gemma":[0.988414,0.0002823395,0.007119841,0.0001435841,0.00002418344,0.00003529956,0.0004718158,0.0002388826,0.003270133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001480429,"threshold_uncertainty_score":0.00495255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01308739525758683,"score_gpt":0.2483602642529174,"score_spread":0.2352728689953305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}