{"id":"W1979085309","doi":"10.1161/circresaha.112.300818","title":"Shear Stress Regulates Endothelial Microparticle Release","year":2013,"lang":"en","type":"article","venue":"Circulation Research","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Kinase; Nitric oxide; Cell biology; Endothelium; Chemistry; Extracellular; Phosphorylation; Biophysics; Molecular biology; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002563882,0.0003574603,0.0002733044,0.0002097247,0.0001403662,0.000522731,0.0001711043,0.0003719958,0.001091963],"category_scores_gemma":[0.0003151213,0.0001312255,0.0002788351,0.0001061887,0.0002248915,0.0003707788,0.0002753671,0.0005210973,0.0002742193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003534799,"about_ca_system_score_gemma":0.0001096101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001328138,"about_ca_topic_score_gemma":0.0001139555,"domain_scores_codex":[0.9998093,0.00004723602,0.00002519634,0.00003597374,0.00004558688,0.00003675385],"domain_scores_gemma":[0.9997044,0.00007562156,0.0001071775,0.00001918716,0.00004859464,0.00004498368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003986522,0.00003808444,0.0008424961,0.0001303026,0.000008311446,0.000120068,0.00002217587,0.00008739165,0.9951757,0.0001323594,0.0001120531,0.002932389],"study_design_scores_gemma":[0.00004315778,0.0007668976,0.0223523,0.00003059151,0.00004499793,0.0004319332,0.00004966592,0.002533976,0.971117,0.0002159287,0.002401994,0.00001147629],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858478,0.007891622,0.003877864,0.0003403973,0.0001206808,0.00006208757,0.0004399378,0.00006700341,0.001352549],"genre_scores_gemma":[0.9937914,0.003003982,0.00194817,0.0001361593,0.00008286989,0.0000603805,0.0002811973,0.000008426586,0.0006873023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001091963,"threshold_uncertainty_score":0.00365299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02918620639973377,"score_gpt":0.3196254415319108,"score_spread":0.290439235132177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}