{"id":"W1979124424","doi":"10.1016/j.ydbio.2007.10.039","title":"Plasticity of proximal–distal cell fate in the mammalian limb bud","year":2007,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Limb bud; Hox gene; Biology; Homeobox; Apical ectodermal ridge; Limb development; Cell fate determination; Zone of polarizing activity; Mesenchyme; Cell biology; Embryonic stem cell; Morphogenesis; Embryo; Anatomy; Embryogenesis; Mesenchymal stem cell; Genetics; Gene; Gene expression; Ectoderm; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005165164,0.0001636616,0.0001532222,0.00007873371,0.00006894537,0.000004560891,0.0002612081,0.0002457147,0.00002621415],"category_scores_gemma":[0.000028964,0.0001222636,0.00005194403,0.0001567472,0.0002194007,0.000003672104,0.0001256919,0.0001011881,0.0000215428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000272063,"about_ca_system_score_gemma":0.00008345434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002076348,"about_ca_topic_score_gemma":0.000230913,"domain_scores_codex":[0.9988306,0.00008491751,0.0003691473,0.0003059193,0.00007212539,0.0003373174],"domain_scores_gemma":[0.999678,0.00003875239,0.0001076228,0.00010486,0.0000312848,0.00003950021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002180981,0.0001096411,0.179759,0.00001363988,0.0000173391,0.000005796585,0.0002008522,0.000001633804,0.8157225,0.0002618325,0.0001604984,0.003529139],"study_design_scores_gemma":[0.000452151,0.000203438,0.3198355,0.00000401384,0.000003410674,0.00003638394,0.0003458989,0.000001128718,0.6696869,0.00008669619,0.009195198,0.0001492809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922644,0.0001225154,0.0006802474,0.0000671212,0.0001339546,0.0002339048,0.00002090068,0.000006232203,0.006470704],"genre_scores_gemma":[0.9968816,0.00002319487,0.002030137,0.000268474,0.00005149997,0.00001461805,0.000447394,0.000008549363,0.0002745374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1460356,"threshold_uncertainty_score":0.4985765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008141845736509305,"score_gpt":0.237958714734851,"score_spread":0.2298168689983417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}