{"id":"W1979140718","doi":"10.1016/j.jss.2012.10.504","title":"Optimizing Steatotic Livers for Transplantation by Upregulation of Heme Oxygenase-1 Fused With a Cell-Penetrating Peptide (CPP)","year":2013,"lang":"en","type":"article","venue":"Journal of Surgical Research","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Heme oxygenase; Transplantation; Liver transplantation; Economic shortage; Downregulation and upregulation; Peptide; Chemistry; Cell; Heme; Medicine; Biochemistry; Internal medicine; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001805527,0.0003766666,0.0002319835,0.0001429808,0.0001354942,0.0003403127,0.0001410865,0.0003277317,0.0009381393],"category_scores_gemma":[0.0001277157,0.0001214409,0.0001486762,0.0001386081,0.0001834281,0.0003341964,0.0002188943,0.0004887131,0.000185132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001910227,"about_ca_system_score_gemma":0.0001754537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001850833,"about_ca_topic_score_gemma":0.000327476,"domain_scores_codex":[0.9998714,0.00001871476,0.00001190695,0.00002501956,0.00003362148,0.00003936797],"domain_scores_gemma":[0.9999181,0.00001370314,0.00003361731,0.000005479848,0.00001193336,0.00001717772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003834648,0.0000120283,0.00004052849,0.00001492625,0.000001249858,0.00001450749,0.000005531076,0.00008022568,0.9992404,0.00005670615,0.00001271141,0.0004829752],"study_design_scores_gemma":[0.000007436636,0.00009617634,0.0005797974,0.000001940536,0.000007770046,0.00008316918,0.00001133074,0.000689649,0.9978752,0.0000259811,0.0006191703,0.000002419259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874682,0.0007686644,0.01050965,0.0001181387,0.00002671645,0.00005324471,0.0001242049,0.0001043751,0.0008268165],"genre_scores_gemma":[0.9936732,0.0003621456,0.004956264,0.00003592371,0.000005253788,0.00002999919,0.0001379265,0.00002399406,0.0007753556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009381393,"threshold_uncertainty_score":0.003138423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02517885764787273,"score_gpt":0.2992495336321783,"score_spread":0.2740706759843056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}