{"id":"W1979167640","doi":"10.1007/s11908-012-0273-5","title":"Toll-Like Receptors and Opportunities for New Sepsis Therapeutics","year":2012,"lang":"en","type":"article","venue":"Current Infectious Disease Reports","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Sepsis; TLR9; Innate immune system; Receptor; Medicine; Immunology; Toll-like receptor; Toll; Immune system; Intensive care medicine; Bioinformatics; Biology; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003295054,0.0001785011,0.0001946976,0.0001122118,0.0002140048,0.00002839778,0.00003507726,0.00011487,0.0002041885],"category_scores_gemma":[0.0001027641,0.0001617609,0.0001244103,0.00004811831,0.00005779417,0.0002517091,0.00003175322,0.0001222152,0.00003464711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007207967,"about_ca_system_score_gemma":0.0001807123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009366506,"about_ca_topic_score_gemma":0.000001125446,"domain_scores_codex":[0.9989531,0.0001060577,0.0003383397,0.0001850197,0.00004261609,0.0003748657],"domain_scores_gemma":[0.9992058,0.0001193979,0.0002386744,0.0002457482,0.00007807629,0.0001123249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005447099,0.0007292051,0.2515994,0.0003450837,0.0008847289,0.00002084028,0.00128765,0.000004553375,0.007754728,0.001534207,0.1741628,0.5611321],"study_design_scores_gemma":[0.0004130287,0.00005464609,0.007264143,0.00004294599,0.0002668668,0.0001422427,0.00006850628,0.00000155101,0.003073284,0.0003618911,0.9880914,0.0002194709],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9125737,0.07073332,0.0006429188,0.0005848304,0.01366113,0.0007016512,0.00001083064,0.0002315912,0.0008599983],"genre_scores_gemma":[0.9885386,0.00393665,0.000007129571,0.0002046535,0.0002357889,0.0001009313,0.0002359485,0.00002555475,0.006714712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8139287,"threshold_uncertainty_score":0.659642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05700240280789874,"score_gpt":0.2966229123341854,"score_spread":0.2396205095262866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}