{"id":"W1979181300","doi":"10.1080/13816810902788974","title":"Why do Cone Photoreceptors Die in Rod-Specific Forms of Retinal Degenerations?","year":2009,"lang":"en","type":"review","venue":"Ophthalmic Genetics","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Autophagy; Retinitis pigmentosa; Retinal; Retina; Programmed cell death; Biology; Cell biology; Retinal degeneration; PI3K/AKT/mTOR pathway; Neuroscience; Apoptosis; Ophthalmology; Genetics; Medicine; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002120976,0.0004935092,0.0009229089,0.0001993226,0.00005223532,0.00003629166,0.0004539325,0.0005436465,0.0000900739],"category_scores_gemma":[0.00003538079,0.0004457321,0.0003523104,0.0002597363,0.0001125098,0.000003210334,0.0001232339,0.0002144941,0.00001993681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004565975,"about_ca_system_score_gemma":0.0002729592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006100317,"about_ca_topic_score_gemma":0.00001503585,"domain_scores_codex":[0.9977477,0.0001107777,0.0008929829,0.00061245,0.0002495143,0.000386558],"domain_scores_gemma":[0.9988432,0.00001904153,0.0003856358,0.0005520227,0.0001014522,0.00009863313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000790328,0.0003397047,0.0007286633,0.002977252,0.0001739925,0.00003756831,0.00008047628,0.00004724969,0.003044831,0.0001118532,0.01355215,0.9788272],"study_design_scores_gemma":[0.0003192883,0.0002859937,0.0001160582,0.001046629,0.00007039107,0.0000635828,0.00002772661,0.000001811081,0.002217451,0.00008448702,0.9952404,0.0005261379],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01347351,0.9822789,0.00006296016,0.00001430575,0.0002351437,0.0006372354,0.00004356369,0.000006115019,0.003248227],"genre_scores_gemma":[0.002215033,0.9944047,0.001526154,0.00004206422,0.0001505156,0.00006247792,0.001155069,0.00006116142,0.0003828771],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9816883,"threshold_uncertainty_score":0.9997994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02932058280863508,"score_gpt":0.2961949979494456,"score_spread":0.2668744151408106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}