{"id":"W1979201160","doi":"10.1016/j.mito.2011.03.089","title":"Endurance exercise reduces mitochondrial DNA random point mutations and reverses the premature aging transcriptome in PolG mutator mouse: I believe in miracle!","year":2011,"lang":"en","type":"article","venue":"Mitochondrion","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Mitochondrial DNA; Point mutation; Transcriptome; Genetics; Biology; Mutation; Premature aging; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002092066,0.0002925558,0.000341096,0.0001833471,0.0001389332,0.00004121569,0.0002430828,0.0003234411,0.00008145557],"category_scores_gemma":[0.0001667165,0.0002394737,0.0001211913,0.0002771217,0.0001904689,0.00003366117,0.00005952552,0.0003434445,0.00001387126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000027258,"about_ca_system_score_gemma":0.00007115669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001563452,"about_ca_topic_score_gemma":0.0008804009,"domain_scores_codex":[0.9980538,0.0002691637,0.0004833185,0.0006277376,0.0001700184,0.0003959657],"domain_scores_gemma":[0.9992582,0.00004264252,0.0001326043,0.0004005765,0.00006417806,0.0001017846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001243756,0.0001233997,0.0006562677,0.00002852527,0.00001754143,0.00002482448,0.004187003,0.00002616415,0.9911819,0.0000539799,0.001611966,0.000844641],"study_design_scores_gemma":[0.009697672,0.0003499865,0.009013704,0.0002976295,0.00008873598,0.0001867265,0.002882136,0.00007542613,0.9627327,0.0006229298,0.01327325,0.0007791578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927622,0.002315093,0.0006326045,0.0006368993,0.001593467,0.001218675,0.0000391279,0.00003211987,0.0007697876],"genre_scores_gemma":[0.9933017,0.0007012583,0.00293963,0.0004596133,0.0004420796,0.0002912046,0.0001219897,0.00004905174,0.00169342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02844928,"threshold_uncertainty_score":0.9765453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295061117493055,"score_gpt":0.2308450659470328,"score_spread":0.2178944547721023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}