{"id":"W1979242839","doi":"10.1021/bi0025215","title":"Contribution of Individual Amino Acids to the Nucleic Acid Binding Activities of the <i>Xenopus</i> Zinc Finger Proteins TFIIIIA and p43","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Zinc finger; Xenopus; Nucleic acid; Zinc; Chemistry; Biochemistry; Zinc finger nuclease; Amino acid; DNA-binding protein; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002488403,0.0004507259,0.0004371591,0.0002488351,0.0002813245,0.0004149869,0.0002487532,0.0003729056,0.0007344888],"category_scores_gemma":[0.0006292124,0.0003696451,0.0003018547,0.0001592136,0.0003379481,0.0002548713,0.0002845817,0.0004729514,0.0003981385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003418086,"about_ca_system_score_gemma":0.0003091175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009625353,"about_ca_topic_score_gemma":0.0008804812,"domain_scores_codex":[0.999702,0.00004552026,0.00002177937,0.00007141223,0.0001000924,0.00005908042],"domain_scores_gemma":[0.9996095,0.00009293121,0.00008775104,0.00003889315,0.00005280427,0.0001181303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007867582,0.00000890824,0.0004583384,0.00002501186,0.000005991557,0.00005685026,0.00001132308,0.00008872483,0.9978591,0.00006138784,0.000009887832,0.001335929],"study_design_scores_gemma":[0.00001335624,0.0001451214,0.01146766,0.000005269328,0.00003470878,0.0007327224,0.00002719949,0.001558407,0.9847826,0.0001213299,0.001102686,0.000008816743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956805,0.001363811,0.002114331,0.00005043956,0.000010419,0.000005281523,0.0000572701,0.00003455488,0.0006833441],"genre_scores_gemma":[0.996389,0.0006294612,0.001889535,0.00003091217,0.000008340759,0.000008952102,0.000202934,0.00003236763,0.0008084096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009625353,"threshold_uncertainty_score":0.00247997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009110872736844671,"score_gpt":0.2429153091235522,"score_spread":0.2338044363867076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}