{"id":"W1979248837","doi":"10.1371/journal.ppat.1003308","title":"Microbes Bind Complement Inhibitor Factor H via a Common Site","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health; Connaught Fund; Academy of Finland","keywords":"Factor H; Biology; Complement system; Microbiology; Alternative complement pathway; Innate immune system; Binding site; Complement control protein; Complement membrane attack complex; Biochemistry; Genetics; Immune system; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006647647,0.0002695958,0.0002476535,0.0002193538,0.0002107056,0.0002695028,0.0002618977,0.0003816446,0.001890397],"category_scores_gemma":[0.0001242052,0.0001462779,0.0003775078,0.0001384574,0.0001612606,0.0002045724,0.0004408373,0.0002904636,0.0005920384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002715947,"about_ca_system_score_gemma":0.0001793675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197917,"about_ca_topic_score_gemma":0.0009747396,"domain_scores_codex":[0.9997949,0.00002426653,0.00000893288,0.00005286793,0.00006721413,0.00005186105],"domain_scores_gemma":[0.9998996,0.00001480754,0.00003338758,0.00001535484,0.00001369348,0.00002313515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006860802,0.00001631558,0.001346231,0.00002104205,0.00001007773,0.00006437879,0.00001461853,0.00003767665,0.9966658,0.0001165127,0.00003560393,0.001603294],"study_design_scores_gemma":[0.00001402484,0.0004734993,0.03548737,0.000009450458,0.00004137064,0.001221682,0.00008333755,0.001059768,0.9567748,0.0001418289,0.004680733,0.00001210036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926563,0.001339733,0.003299254,0.00006593498,0.00001531522,0.00002127014,0.0002141634,0.00005540983,0.002332561],"genre_scores_gemma":[0.9944729,0.0002360829,0.003531005,0.00008000161,0.00000487765,0.000008412236,0.000211122,0.0000063575,0.001449206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001890397,"threshold_uncertainty_score":0.006323993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02090368713677965,"score_gpt":0.2332849213696822,"score_spread":0.2123812342329025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}