{"id":"W1979300135","doi":"10.1016/j.bmcl.2011.12.097","title":"Structurally diverse disaccharide analogs of antifreeze glycoproteins and their ability to inhibit ice recrystallization","year":2011,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Disaccharide; Chemistry; Galactosamine; Recrystallization (geology); Monosaccharide; Glycoprotein; Stereochemistry; Antifreeze protein; Antifreeze; Biochemistry; Organic chemistry; Galactose","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001260063,0.0002097707,0.0001649905,0.0001009032,0.00008819218,0.0001721963,0.0002469252,0.000194098,0.0009178656],"category_scores_gemma":[0.0001478691,0.0001046561,0.0001439953,0.0001336224,0.0001875221,0.0001573248,0.000094009,0.0004859945,0.0001196318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001864274,"about_ca_system_score_gemma":0.0001514648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001515386,"about_ca_topic_score_gemma":0.001846612,"domain_scores_codex":[0.9999443,0.000009508663,0.000004087972,0.000006290275,0.0000130162,0.00002281086],"domain_scores_gemma":[0.9999391,0.00001572734,0.0000130425,0.000008125775,0.000008088231,0.00001601635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004659814,0.00007064074,0.0001577198,0.00002851437,0.000009641491,0.00004782743,0.000029913,0.0003867515,0.9967399,0.0001539238,0.00007114748,0.001837991],"study_design_scores_gemma":[0.00004375813,0.0006918532,0.00152345,0.000002708372,0.00001260753,0.00009741441,0.00001996765,0.0003299575,0.9956396,0.00002516986,0.001608822,0.000004616755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976896,0.0008348872,0.0004042909,0.00003560752,0.00001264241,0.00001659128,0.0001266006,0.00001379138,0.0008659521],"genre_scores_gemma":[0.9972827,0.0006459326,0.0005454627,0.00003111157,0.000003941934,0.00000943448,0.000363371,0.000008930903,0.001109032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001515386,"threshold_uncertainty_score":0.003070533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01940672644965351,"score_gpt":0.1970993748201423,"score_spread":0.1776926483704888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}