{"id":"W1979339333","doi":"10.1089/scd.2012.0204","title":"Human Embryonic Stem Cell-Derived Hematopoietic Cells Maintain Core Epigenetic Machinery of the Polycomb Group/Trithorax Group Complexes Distinctly from Functional Adult Hematopoietic Stem Cells","year":2012,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Embryonic stem cell; Stem cell; Haematopoiesis; Epigenetics; Progenitor cell; Induced pluripotent stem cell; Cell biology; Myeloid; Cellular differentiation; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001020188,0.0001600204,0.0001106528,0.0001529445,0.00008389429,0.0002237092,0.00008059011,0.00009774737,0.001073351],"category_scores_gemma":[0.00009354106,0.00007884735,0.00008254351,0.0001517351,0.000193879,0.0001055543,0.0001416555,0.0002081147,0.0004833088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009668204,"about_ca_system_score_gemma":0.000157194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002824,"about_ca_topic_score_gemma":0.0005051233,"domain_scores_codex":[0.999926,0.00001040504,0.0000073824,0.00001699841,0.00002856261,0.00001065241],"domain_scores_gemma":[0.9999448,0.000008720486,0.00001278265,0.00001523194,0.000008872626,0.000009607779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001402648,0.000003086811,0.0004390601,0.00001478474,0.000002487977,0.00002085796,0.00001224958,0.00003025873,0.9970041,0.0001867789,0.00001935289,0.002252926],"study_design_scores_gemma":[0.000004610617,0.0000782449,0.02001481,0.000005157662,0.00001282748,0.000314056,0.00003343451,0.0003698318,0.9716059,0.0001611945,0.007397165,0.000002687906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9690825,0.001958712,0.02185169,0.00009347951,0.00002449219,0.0000677541,0.001297638,0.0002218086,0.005401858],"genre_scores_gemma":[0.9849776,0.001292059,0.00680669,0.00004405079,0.00000918709,0.0000345974,0.001912797,0.00003109067,0.004891977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001073351,"threshold_uncertainty_score":0.003590763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0204634334876799,"score_gpt":0.2360761430667632,"score_spread":0.2156127095790834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}