{"id":"W1979339333","doi":"10.1089/scd.2012.0204","title":"Human Embryonic Stem Cell-Derived Hematopoietic Cells Maintain Core Epigenetic Machinery of the Polycomb Group/Trithorax Group Complexes Distinctly from Functional Adult Hematopoietic Stem Cells","year":2012,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Embryonic stem cell; Stem cell; Haematopoiesis; Epigenetics; Progenitor cell; Induced pluripotent stem cell; Cell biology; Myeloid; Cellular differentiation; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000653072,0.0007169325,0.0007214734,0.0001219756,0.0006054075,0.00009455923,0.0007230802,0.0003523452,0.0001169428],"category_scores_gemma":[0.000002000944,0.0005672539,0.0002665635,0.0002404908,0.0003771828,0.00002199641,0.001056366,0.0003798376,0.00008520911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001346667,"about_ca_system_score_gemma":0.0001918404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009870099,"about_ca_topic_score_gemma":0.00009258177,"domain_scores_codex":[0.9955192,0.0004034798,0.00105161,0.0009800558,0.0009257557,0.001119897],"domain_scores_gemma":[0.99777,0.0001171747,0.0005088431,0.0009272304,0.0001787593,0.0004979743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001217696,0.0005033095,0.005718829,0.0005693767,0.0001757839,0.000008683071,0.0005638031,0.00006038507,0.9898257,0.0001795853,0.001099678,0.001173086],"study_design_scores_gemma":[0.001552494,0.0002046226,0.01108035,0.0001739465,0.00006429697,0.00002411512,0.001459559,0.00006391474,0.9806213,0.00005768074,0.003944475,0.0007532167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904113,0.004828185,0.00226275,0.00005756363,0.0007689336,0.001079367,0.0002163839,0.00003546883,0.0003400742],"genre_scores_gemma":[0.995232,0.0002812601,0.001028302,0.0001494806,0.0001866459,0.0001090868,0.0001906663,0.0001056788,0.002716917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009204384,"threshold_uncertainty_score":0.9996779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0204634334876799,"score_gpt":0.2360761430667632,"score_spread":0.2156127095790834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}