{"id":"W1979358788","doi":"10.1111/j.1524-475x.2007.00210.x","title":"Keratinocyte conditioned medium abrogates the modulatory effects of IGF‐1 and TGF‐β1 on collagenase expression in dermal fibroblasts","year":2007,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Keratinocyte; Collagenase; Transforming growth factor; Extracellular matrix; Wound healing; Western blot; Fibrosis; Matrix metalloproteinase; Blot; Biology; Chemistry; Medicine; Pathology; Cell biology; Immunology; Internal medicine; Cell culture; Biochemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001422355,0.0004588609,0.0003344278,0.000233598,0.0001550347,0.0002712669,0.0001554544,0.000186599,0.0012548],"category_scores_gemma":[0.0001119317,0.0001638861,0.0002494229,0.0001240597,0.000243192,0.0001262564,0.0001803201,0.0005508631,0.0003085818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003091867,"about_ca_system_score_gemma":0.0002984429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001805392,"about_ca_topic_score_gemma":0.002949676,"domain_scores_codex":[0.9998122,0.00002974775,0.00002316125,0.00002909172,0.00004595971,0.00005989437],"domain_scores_gemma":[0.9998322,0.00004537746,0.00003183657,0.00002440513,0.00001906372,0.00004712915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001305676,0.00003179783,0.00009376621,0.00002621239,0.000002434238,0.00002735493,0.00001358892,0.00001319416,0.9991221,0.00001367558,0.00001251003,0.0005129167],"study_design_scores_gemma":[0.0000221517,0.0005496992,0.006750775,0.000008903046,0.0000122768,0.0001356523,0.00003675182,0.000272615,0.9909669,0.0000142,0.001226012,0.000004068061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952756,0.002251737,0.0007490756,0.00006741541,0.00006260897,0.00003214374,0.0003243349,0.00003458058,0.001202475],"genre_scores_gemma":[0.9951067,0.001089102,0.00102709,0.00005415338,0.00001432119,0.00003932906,0.0005156829,0.000007836746,0.002145798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001805392,"threshold_uncertainty_score":0.004197717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003822783630926296,"score_gpt":0.2340236938938301,"score_spread":0.2302009102629038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}