{"id":"W1979444473","doi":"10.1158/1538-7445.am2012-3687","title":"Abstract 3687: An integrative genomics approach identifies distinct molecular and epigenetic subgroups of pediatric glioblastoma","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Epigenetics; Biology; Transcriptome; Methylation; DNA methylation; Genomics; Genetics; Gene; Genome; Computational biology; Cancer research; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001641055,0.0003331377,0.0003900016,0.0005895357,0.0001352317,0.0002521591,0.0001685192,0.0001393404,0.000937295],"category_scores_gemma":[0.0001428235,0.0001401734,0.0003250114,0.0004002547,0.000148547,0.00008706088,0.0002715424,0.0002384501,0.0001831185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002160778,"about_ca_system_score_gemma":0.0003022579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001155541,"about_ca_topic_score_gemma":0.002037238,"domain_scores_codex":[0.9998935,0.00001396482,0.000003532817,0.00004028884,0.00001810655,0.00003050721],"domain_scores_gemma":[0.9999474,0.00001313247,0.00001784462,0.00000582375,0.000006212411,0.000009532881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002004669,0.00004347939,0.01241216,0.0000401512,0.00003064629,0.0001067159,0.00008835038,0.0003347295,0.9766775,0.0001279247,0.00008926838,0.009848544],"study_design_scores_gemma":[0.00005347253,0.001030127,0.6918727,0.00001766506,0.0003111717,0.001733645,0.0003504078,0.01110569,0.2884139,0.0004618296,0.004625169,0.00002419472],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932284,0.0002681246,0.005213816,0.00003134142,0.00000292873,0.00003147324,0.0007620162,0.00005943372,0.0004024667],"genre_scores_gemma":[0.9820158,0.0003482878,0.01392737,0.00005027186,0.000007103637,0.00004799441,0.003021785,0.00003023164,0.0005510004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001155541,"threshold_uncertainty_score":0.003135502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05168068183011822,"score_gpt":0.3742201428664457,"score_spread":0.3225394610363275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}