{"id":"W1979493235","doi":"10.1016/j.molimm.2010.09.007","title":"The PH domain adaptor protein Bam32/DAPP1 functions in mast cells to restrain FcɛRI-induced calcium flux and granule release","year":2010,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"LYN; Degranulation; Cell biology; Mast cell; Phosphorylation; Wortmannin; Signal transduction; Kinase; Signal transducing adaptor protein; Chemistry; Tyrosine phosphorylation; Protein kinase B; Proto-oncogene tyrosine-protein kinase Src; Receptor; Biology; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002099059,0.000262485,0.0001840062,0.0001785232,0.0002884312,0.0003418339,0.0002180023,0.0003088144,0.001324407],"category_scores_gemma":[0.0001546425,0.0002064213,0.0001792314,0.0001402437,0.0002064388,0.0003267929,0.0003325098,0.0006529058,0.000648785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003822469,"about_ca_system_score_gemma":0.0002186732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001763119,"about_ca_topic_score_gemma":0.0002687092,"domain_scores_codex":[0.9999152,0.00001064048,0.000006104572,0.00001725725,0.00002062542,0.00003010044],"domain_scores_gemma":[0.9999275,0.000008272405,0.00002063913,0.000009308884,0.00000645483,0.00002788736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002053494,0.00001432371,0.0002060204,0.00003935706,0.000003737132,0.000104871,0.000006792729,0.00007026036,0.9971739,0.0001653294,0.0001350749,0.00187501],"study_design_scores_gemma":[0.00009399823,0.0001589386,0.01196863,0.000005128643,0.00001387077,0.0006712432,0.00002985564,0.001377955,0.9811984,0.0002603279,0.004215355,0.000006170645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893236,0.00368527,0.003886895,0.0005071757,0.00007153166,0.00002892277,0.0004741503,0.0001812554,0.001841252],"genre_scores_gemma":[0.9950917,0.0009310026,0.00137885,0.00005292507,0.00001636604,0.00002578053,0.0004374386,0.0000181553,0.002047786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001324407,"threshold_uncertainty_score":0.004430592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006857618985192176,"score_gpt":0.2318426769518668,"score_spread":0.2249850579666746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}