{"id":"W1979535340","doi":"10.1111/j.1600-0765.2007.01049.x","title":"Macrophage tolerance response to <i>Aggregatibacter actinomycetemcomitans</i> lipopolysaccharide induces differential regulation of tumor necrosis factor‐α, interleukin‐1β and matrix metalloproteinase 9 secretion","year":2008,"lang":"en","type":"article","venue":"Journal of Periodontal Research","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Aggregatibacter actinomycetemcomitans; Lipopolysaccharide; Tumor necrosis factor alpha; Secretion; Interleukin; U937 cell; Macrophage; Immunology; Chemistry; Biology; Internal medicine; Cytokine; Endocrinology; Porphyromonas gingivalis; Medicine; Cell culture; Periodontitis; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001385706,0.0003337389,0.0002218528,0.0001155931,0.0001134353,0.0002444331,0.00007134883,0.0002082193,0.0007068763],"category_scores_gemma":[0.00009758151,0.0001016609,0.0002342448,0.00009211486,0.0001472689,0.0001031735,0.0001406093,0.0002833172,0.0002657902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001556881,"about_ca_system_score_gemma":0.00009768586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002029922,"about_ca_topic_score_gemma":0.000195568,"domain_scores_codex":[0.9998826,0.00002151569,0.00001464947,0.00001581102,0.00002186902,0.00004360558],"domain_scores_gemma":[0.9999044,0.00001110976,0.00003999355,0.00001010851,0.00001375198,0.00002061136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001491782,0.00001841798,0.0003951171,0.00002251831,0.000002928342,0.00008220823,0.00001377603,0.00001111244,0.9988874,0.00001051996,0.00001576412,0.0003910093],"study_design_scores_gemma":[0.00004320157,0.00176029,0.031836,0.0000125662,0.0000312559,0.001289243,0.000128677,0.0003115516,0.9633964,0.00004385951,0.001139652,0.000007362994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986115,0.0006286232,0.0003027991,0.00003291369,0.00001279967,0.00001075646,0.00006249185,0.00001637327,0.000321699],"genre_scores_gemma":[0.9986896,0.0003507671,0.0003339445,0.00005680688,0.00001443261,0.00001989064,0.0001817783,0.000003535617,0.0003492547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007068763,"threshold_uncertainty_score":0.002364755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04465844466171881,"score_gpt":0.343292253714547,"score_spread":0.2986338090528282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}