{"id":"W1979535340","doi":"10.1111/j.1600-0765.2007.01049.x","title":"Macrophage tolerance response to <i>Aggregatibacter actinomycetemcomitans</i> lipopolysaccharide induces differential regulation of tumor necrosis factor‐α, interleukin‐1β and matrix metalloproteinase 9 secretion","year":2008,"lang":"en","type":"article","venue":"Journal of Periodontal Research","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Aggregatibacter actinomycetemcomitans; Lipopolysaccharide; Tumor necrosis factor alpha; Secretion; Interleukin; U937 cell; Macrophage; Immunology; Chemistry; Biology; Internal medicine; Cytokine; Endocrinology; Porphyromonas gingivalis; Medicine; Cell culture; Periodontitis; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001944068,0.0002699991,0.0007115792,0.000833364,0.0004572961,0.0001925743,0.0005837562,0.0002496918,0.001689112],"category_scores_gemma":[0.001112133,0.0002299818,0.0002679283,0.0004618626,0.0006250364,0.0006980736,0.0003673255,0.001342857,0.00006617169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002750484,"about_ca_system_score_gemma":0.0003516823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004101685,"about_ca_topic_score_gemma":0.0002063585,"domain_scores_codex":[0.9955618,0.0014032,0.0009769248,0.0003966307,0.001044198,0.0006172549],"domain_scores_gemma":[0.9973664,0.0004860108,0.0004361734,0.000368895,0.0009455347,0.0003969348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01079556,0.0001471515,0.02090163,0.00009749053,0.00008972689,0.000588243,0.001602057,0.000002290883,0.963726,0.00001863973,0.0002410482,0.001790096],"study_design_scores_gemma":[0.001297306,0.001237986,0.4247167,0.0002442234,0.00001478506,0.002117092,0.0003515936,0.0000203729,0.5690426,0.00003152601,0.0007370613,0.0001887919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980544,0.0004838416,0.00007686595,0.0003123555,0.000417654,0.0004870296,0.0001163576,0.00001300009,0.00003851094],"genre_scores_gemma":[0.9970915,0.0001067911,0.0005293345,0.00002324372,0.0002590996,0.00001595863,0.000007290081,0.00003888976,0.00192793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4038151,"threshold_uncertainty_score":0.9992235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04465844466171881,"score_gpt":0.343292253714547,"score_spread":0.2986338090528282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}