{"id":"W1979579157","doi":"10.1002/jps.22449","title":"COMMENTARY: Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Lamivudine","year":2011,"lang":"en","type":"review","venue":"Journal of Pharmaceutical Sciences","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"World Health Organization","keywords":"Biopharmaceutics Classification System; Bioequivalence; Lamivudine; Pharmacology; Active ingredient; Bioavailability; Dosage form; Drug; Biopharmaceutics; Dissolution testing; Medicine; Chemistry; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006835538,0.001897111,0.003344008,0.002288884,0.00206287,0.003450883,0.004197528,0.04381913,0.01166567],"category_scores_gemma":[0.02594664,0.001191298,0.002345511,0.002268161,0.002841321,0.003815842,0.002844651,0.03233146,0.01086602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005404972,"about_ca_system_score_gemma":0.009063521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006643794,"about_ca_topic_score_gemma":0.01382835,"domain_scores_codex":[0.9953691,0.001086216,0.0008530242,0.0004807416,0.001783987,0.0004268543],"domain_scores_gemma":[0.9809179,0.009431982,0.003126315,0.0003559532,0.004677573,0.001490199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004509435,0.000006676559,0.00001578821,0.0004632736,0.00001701232,0.0000786296,0.00002027778,0.00001401066,0.00009140446,0.0002747638,0.9921654,0.006807701],"study_design_scores_gemma":[0.000129631,0.00004055475,0.0002168405,0.001537927,0.00009409886,0.0002069406,0.00004416293,0.00004516743,0.0001139296,0.0006786956,0.9968696,0.00002244303],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001297083,0.03748994,0.0001369835,0.7149581,0.244474,0.00005815062,0.0003184247,0.00004856794,0.002386191],"genre_scores_gemma":[0.0010655,0.01809739,0.0002330135,0.8401851,0.1294048,0.00008651862,0.0001178017,0.00003521207,0.01077467],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04381913,"threshold_uncertainty_score":0.03921604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1574831537308598,"score_gpt":0.4528296627799481,"score_spread":0.2953465090490882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}