{"id":"W1979603195","doi":"10.1111/jnc.12316","title":"Specific subcellular changes in oxidative stress in prefrontal cortex from patients with bipolar disorder","year":2013,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Toronto; University of Manitoba; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Peroxynitrite; Oxidative stress; Nitrotyrosine; Lipid peroxidation; Protein Carbonylation; Mitochondrion; Chemistry; Prefrontal cortex; Oxidative phosphorylation; Bipolar disorder; Biochemistry; Internal medicine; Endocrinology; Biology; Nitric oxide synthase; Neuroscience; Superoxide; Medicine; Enzyme; Lithium (medication)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003752585,0.0001867752,0.0002478166,0.0001173781,0.00002894431,0.00005402149,0.0003755323,0.00007305641,0.0002730639],"category_scores_gemma":[0.000121223,0.0001498178,0.00004520126,0.0002660209,0.00009906798,0.0002854,0.00005478811,0.0004484424,0.0000124532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004779592,"about_ca_system_score_gemma":0.0000347885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004435852,"about_ca_topic_score_gemma":0.00006016493,"domain_scores_codex":[0.9986501,0.00007037733,0.0003307722,0.0002891723,0.000392817,0.0002668138],"domain_scores_gemma":[0.9992197,0.000132357,0.0003031343,0.0001796343,0.00006000848,0.0001052182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00009992413,0.000501941,0.1305017,0.00001332434,0.000003389446,0.00009173458,0.0002606164,0.00001574075,0.8675097,9.570269e-7,0.00008659626,0.0009143595],"study_design_scores_gemma":[0.00168355,0.0001468398,0.5782429,0.00008512283,0.000002432065,0.000006740481,0.0002634975,0.00002387515,0.4188673,0.00005378466,0.0004771852,0.0001467066],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990268,0.000345153,0.00001225091,0.0001561508,0.0001003171,0.0001633408,0.00003147433,0.000007763443,0.0001568003],"genre_scores_gemma":[0.9995266,0.0001336027,0.00005447725,0.0001335908,0.00006238608,0.000005476672,0.00000718721,0.00002208105,0.00005462841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4486423,"threshold_uncertainty_score":0.6109393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009796861015192357,"score_gpt":0.2014626624858964,"score_spread":0.191665801470704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}