{"id":"W1979605220","doi":"10.1021/jf200293e","title":"Thermal Generation of 3-Amino-4,5-dimethylfuran-2(5<i>H</i>)-one, the Postulated Precursor of Sotolone, from Amino Acid Model Systems Containing Glyoxylic and Pyruvic Acids","year":2011,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Natural Products and Biological Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Glyoxylic acid; Pyruvic acid; Chemistry; Acetaldehyde; Aldol condensation; Formaldehyde; Maillard reaction; Organic chemistry; Malonic acid; Glyoxal; Aldehyde; Aldol reaction; Acetoin; Glycine; Amino acid; Biochemistry; Ethanol; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270863,0.0003177268,0.0001137538,0.0001167061,0.0001136798,0.0001193207,0.0001657585,0.0002266294,0.0006626268],"category_scores_gemma":[0.00009413521,0.00009304898,0.0002581959,0.00008581903,0.000109385,0.0001684207,0.0001476059,0.0002712456,0.0002295816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002429142,"about_ca_system_score_gemma":0.0001985729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004825895,"about_ca_topic_score_gemma":0.0007680653,"domain_scores_codex":[0.9999323,0.00001049443,0.000003196217,0.00001651811,0.00001509652,0.0000222781],"domain_scores_gemma":[0.9999462,0.000006978721,0.0000170089,0.000007286097,0.00001015478,0.00001229358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004744176,0.000007396058,0.0001071233,0.00002911574,0.000003158496,0.00004037708,0.00001445771,0.00008550697,0.9985461,0.0001541901,0.00002216633,0.0009428351],"study_design_scores_gemma":[0.00000247337,0.00007770917,0.0003644419,0.00000127499,0.000002892728,0.00003648483,0.000006048278,0.0002930519,0.9985883,0.00002140261,0.0006031571,0.000002741267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832584,0.001010176,0.01232751,0.00006742526,0.00005728969,0.00005364635,0.0002450551,0.00009400585,0.002886544],"genre_scores_gemma":[0.9929497,0.0003248043,0.005004882,0.000026198,0.000005818782,0.00002215692,0.0001999593,0.00001249287,0.001454034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006626268,"threshold_uncertainty_score":0.002216697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.063691970447036,"score_gpt":0.2524294336151711,"score_spread":0.1887374631681351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}