{"id":"W1979623506","doi":"10.1016/j.matbio.2015.01.018","title":"EMMPRIN, an upstream regulator of MMPs, in CNS biology","year":2015,"lang":"en","type":"review","venue":"Matrix Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Regulator; Metalloproteinase; Neuroscience; Homeostasis; Central nervous system; Integrin; Multiple sclerosis; Cell adhesion molecule; Extracellular matrix; Medicine; Immunology; Biology; Cell biology; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000238958,0.0005356087,0.0005753044,0.001124408,0.0002209145,0.0006663717,0.0003928214,0.0006401919,0.002583387],"category_scores_gemma":[0.0002878486,0.0001523395,0.0002620904,0.001239158,0.0002785924,0.0009145178,0.0004765408,0.00096256,0.001425567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004362901,"about_ca_system_score_gemma":0.0007143272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005064068,"about_ca_topic_score_gemma":0.0009156095,"domain_scores_codex":[0.9999226,0.0000105089,0.00001066655,0.00001525951,0.00003089873,0.0000101238],"domain_scores_gemma":[0.9999045,0.00003590388,0.00001394182,0.000003525791,0.00002866219,0.00001349854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007962222,0.00005278314,0.0002582079,0.01049299,0.00005264429,0.000262285,0.00008495131,0.0003691579,0.007205604,0.005348016,0.01735631,0.9584374],"study_design_scores_gemma":[0.000007479271,0.00007051932,0.001180285,0.001566576,0.00006829775,0.00131158,0.00006654311,0.00009123686,0.001734202,0.002247627,0.9916428,0.00001290359],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004243409,0.9968283,0.000259126,0.0002618307,0.0001565402,0.000003772455,0.00002190513,0.00001317613,0.002031052],"genre_scores_gemma":[0.001601099,0.9967958,0.0002609121,0.0001049485,0.00008605044,0.000004248002,0.00002794733,0.000001680737,0.001117303],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002583387,"threshold_uncertainty_score":0.008642256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05639088614204475,"score_gpt":0.4075042400504199,"score_spread":0.3511133539083752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}