{"id":"W1979706247","doi":"10.1038/leu.2013.40","title":"Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia","year":2013,"lang":"en","type":"article","venue":"Leukemia","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"GRB2; Signal transducing adaptor protein; Downstream (manufacturing); Cancer research; Leukemia; Lymphoid leukemia; breakpoint cluster region; Biology; Cell biology; Immunology; Signal transduction; Receptor; Genetics; Business","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000290198,0.0007141589,0.001286858,0.0003378278,0.0001506067,0.00004300171,0.0004390482,0.0007490616,0.002613865],"category_scores_gemma":[0.0005303952,0.0006245859,0.0005388614,0.0007202374,0.0003261941,0.0003709078,0.000147147,0.0003924171,0.001215525],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01004095,"about_ca_system_score_gemma":0.00443753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003066733,"about_ca_topic_score_gemma":0.00003168724,"domain_scores_codex":[0.9956546,0.00007355634,0.001372864,0.0009950754,0.0007782272,0.001125673],"domain_scores_gemma":[0.9963183,0.0004901687,0.000583089,0.001479602,0.0005180821,0.0006107171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002588312,0.001127336,0.03914778,0.002178918,0.004295309,0.0002416942,0.003733404,0.0001984769,0.4330645,0.0008049553,0.4463561,0.06626318],"study_design_scores_gemma":[0.1554952,0.006681299,0.06639513,0.004251473,0.004259387,0.001518879,0.001775772,0.07816955,0.5698607,0.002972628,0.1043213,0.004298734],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852385,0.001020113,0.0001031752,0.0007004572,0.0005217404,0.00299021,0.0003201166,0.0004000745,0.008705609],"genre_scores_gemma":[0.9790997,0.0002962443,0.003374013,0.001110851,0.0003206723,0.0006075443,0.001010903,0.0001885571,0.0139915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3420348,"threshold_uncertainty_score":0.9996206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0154479811503089,"score_gpt":0.2532939612142027,"score_spread":0.2378459800638938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}