{"id":"W1979754115","doi":"10.1182/blood-2011-11-393272","title":"Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; University of Toronto; Ontario Institute for Cancer Research; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Cytokinesis; Biology; Stem cell; Cell biology; Asymmetric cell division; Progenitor cell; Cell division; Haematopoiesis; Cell fate determination; Hematopoietic stem cell; Cell; Genetics; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000159861,0.0001752392,0.0001623553,0.0002969931,0.0001738378,0.0004391883,0.0001698403,0.0001902939,0.0007738984],"category_scores_gemma":[0.0001888299,0.0001260704,0.0001499573,0.0002476235,0.0002132197,0.000250861,0.0002652839,0.0003672605,0.0002841907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002486214,"about_ca_system_score_gemma":0.0001253639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002538179,"about_ca_topic_score_gemma":0.0003335159,"domain_scores_codex":[0.9998078,0.00002485226,0.00001324585,0.00003584253,0.00008311715,0.00003526443],"domain_scores_gemma":[0.9998893,0.00001814654,0.00002910218,0.0000236886,0.00001566615,0.00002415941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003790128,0.000006568623,0.0006890933,0.000006858138,0.000002223422,0.00003393819,0.000006957892,0.00003339345,0.9980082,0.0001178594,0.000009976706,0.001047006],"study_design_scores_gemma":[0.00000671104,0.00006975573,0.01117547,0.000001330818,0.000008588939,0.0004269663,0.00003310357,0.001763846,0.9853154,0.0001365692,0.001060096,0.000002156219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952413,0.0004844792,0.003495576,0.00003056927,0.000003996976,0.000006617881,0.00008198475,0.00001619223,0.0006393244],"genre_scores_gemma":[0.9970874,0.000177691,0.001534514,0.00001754052,0.000003229604,0.00001169459,0.0002464343,0.000008495982,0.0009130401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007738984,"threshold_uncertainty_score":0.002588987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01536480160844839,"score_gpt":0.2091339945245124,"score_spread":0.193769192916064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}