{"id":"W1979754402","doi":"10.1021/jo015751d","title":"Evidence for the Biosynthesis of Squalene via the Methylerythritol Phosphate Pathway in a <i>Streptomyces</i> sp. Obtained from a Marine Sediment","year":2001,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Squalene; Phosphate; Biosynthesis; Streptomyces; Stereochemistry; Sediment; Environmental chemistry; Biochemistry; Enzyme; Paleontology; Geology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001428132,0.0002479441,0.0003200931,0.00001347152,0.0001192118,0.00002133512,0.001081279,0.0001549363,0.0003619988],"category_scores_gemma":[0.0007794493,0.0001258418,0.0002411199,0.0002067553,0.0001936734,0.000009957958,0.0002249121,0.0002493281,0.000001449405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004043266,"about_ca_system_score_gemma":0.0001936571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000612156,"about_ca_topic_score_gemma":0.00003253265,"domain_scores_codex":[0.9984378,0.0001036692,0.0006526567,0.0002184861,0.0003048184,0.0002825525],"domain_scores_gemma":[0.9973931,0.001063504,0.0006660889,0.0006365504,0.0001693926,0.00007130705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001168042,0.0001148335,0.001262478,0.00004512424,0.0002394597,0.000009993163,0.00008179121,0.00001831265,0.9924527,2.437688e-7,0.0004094024,0.004197631],"study_design_scores_gemma":[0.0006372797,0.00009062784,0.000820484,0.0001752475,0.0001828558,0.0002967547,0.0004296026,0.00005205908,0.9931447,0.00005468972,0.00395672,0.0001589828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882677,0.007724318,0.0005546475,0.003008952,0.00008974367,0.0002072096,0.00005701378,0.000004429479,0.00008605086],"genre_scores_gemma":[0.9939978,0.004825765,0.0001936864,0.0002176428,0.0004821639,0.000008427196,0.00001437443,0.00002182426,0.0002383567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005730124,"threshold_uncertainty_score":0.5131679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01817664609324093,"score_gpt":0.2396026287652008,"score_spread":0.2214259826719599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}