{"id":"W1979759452","doi":"10.1016/j.yexcr.2014.10.007","title":"ATF6β regulates the Wfs1 gene and has a cell survival role in the ER stress response in pancreatic β-cells","year":2014,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Canada Research Chairs; University Health Network","keywords":"ATF6; Unfolded protein response; XBP1; Biology; Endoplasmic reticulum; Activating transcription factor; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001533329,0.0001565641,0.0001397735,0.00006956069,0.0001860987,0.0001276407,0.0003981869,0.00009455026,0.00003437035],"category_scores_gemma":[0.00007507248,0.0000992854,0.00005062036,0.0001551855,0.0003752618,0.000005707936,0.000281126,0.0002378225,0.00001519597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002638706,"about_ca_system_score_gemma":0.00007090032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00041861,"about_ca_topic_score_gemma":0.00008737012,"domain_scores_codex":[0.9971101,0.001446459,0.0001949311,0.0004022855,0.0003913562,0.0004548563],"domain_scores_gemma":[0.9989833,0.0003209711,0.00003238524,0.0005312585,0.00003182905,0.0001002561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001075535,0.0003341623,0.005505377,0.00001806128,0.000004386418,0.00001813048,0.001105455,0.00006313049,0.9911858,0.00002809059,0.0006032772,0.00005857861],"study_design_scores_gemma":[0.0011126,0.0004189646,0.006884334,0.00001495517,0.000003077777,0.00000294197,0.005599308,0.0003982953,0.9822136,0.00004826253,0.00317518,0.0001284792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990039,0.005323438,0.000002978502,0.0002667283,0.00003706338,0.0003885171,0.00001394894,0.000003350978,0.003924986],"genre_scores_gemma":[0.9985261,0.0002274752,0.00004051606,0.00008874502,0.00008636751,0.000126873,0.00002736097,0.00002039104,0.0008561491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008972214,"threshold_uncertainty_score":0.4048741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02185869930898608,"score_gpt":0.3057066840485764,"score_spread":0.2838479847395903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}