{"id":"W1979816280","doi":"10.1038/nature08638","title":"Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":1645,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"U.S. Public Health Service; National Institutes of Health; Howard Hughes Medical Institute","keywords":"breakpoint cluster region; B-cell receptor; Lymphoma; B cell; Biology; Diffuse large B-cell lymphoma; Cancer research; PAX5; Receptor; Antibody; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003869182,0.0001439908,0.0002957991,0.0003325567,0.0001970933,0.0006283703,0.0001970914,0.000394919,0.0009269998],"category_scores_gemma":[0.0004513459,0.0001316676,0.0001047562,0.0003585747,0.0003875284,0.0003835473,0.0002148754,0.0004183602,0.0003070646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004196743,"about_ca_system_score_gemma":0.0002588367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004532276,"about_ca_topic_score_gemma":0.0007440414,"domain_scores_codex":[0.9998764,0.00004376058,0.00001595435,0.00001102363,0.0000243003,0.00002849014],"domain_scores_gemma":[0.9998057,0.00006275962,0.00005139701,0.00001473957,0.00002000752,0.00004542532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01390083,0.0009120585,0.329123,0.00176143,0.0001894628,0.020017,0.0007298339,0.0006907082,0.2631564,0.008116481,0.0101454,0.3512574],"study_design_scores_gemma":[0.001453525,0.005802306,0.7194554,0.0002767122,0.0004422995,0.1065954,0.001146716,0.00206112,0.02951197,0.007711896,0.1254877,0.00005502929],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9092746,0.07742121,0.0008336176,0.001609208,0.0001440771,0.00002441484,0.0001256872,0.0000382896,0.01052893],"genre_scores_gemma":[0.9889523,0.008552197,0.0003443779,0.0002767629,0.0002915554,0.00001595191,0.0001476443,0.000006576363,0.001412691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009269998,"threshold_uncertainty_score":0.00310111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004481336229919334,"score_gpt":0.2448041591636851,"score_spread":0.2403228229337658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}