{"id":"W1979861016","doi":"10.1016/s0898-6568(03)00056-1","title":"Activation of ERK1/2 by platelet-activating factor receptor is independent of receptor internalisation and G-protein activation","year":2003,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Cell biology; G protein-coupled receptor; G protein-coupled receptor kinase; Phosphorylation; Arrestin; MAPK/ERK pathway; Receptor; Signal transduction; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003427444,0.0007117711,0.000410208,0.0003776599,0.0002978639,0.0008118764,0.0004162887,0.0003717625,0.00252451],"category_scores_gemma":[0.0003752182,0.0003431567,0.0008032324,0.0002628959,0.0003746861,0.0007108001,0.0006256283,0.00120988,0.001340045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005253079,"about_ca_system_score_gemma":0.0003792961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004523286,"about_ca_topic_score_gemma":0.0006583228,"domain_scores_codex":[0.9996544,0.00004877355,0.00001992581,0.00003295868,0.00008232715,0.0001615618],"domain_scores_gemma":[0.9998211,0.00004628152,0.00003315587,0.00004409118,0.00002378622,0.00003151845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001053505,0.0001064475,0.0002291394,0.0001606797,0.00002353727,0.0003015222,0.00002741857,0.00009805567,0.9933386,0.001496597,0.0002590622,0.002905363],"study_design_scores_gemma":[0.0001475327,0.0003055654,0.01524368,0.00002129264,0.00003060996,0.001348895,0.0000446023,0.001321577,0.9765351,0.0005608848,0.004422097,0.00001819847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732904,0.005726029,0.007526349,0.0005625496,0.0001527848,0.00017756,0.001191686,0.0003002947,0.01107232],"genre_scores_gemma":[0.9839084,0.002606692,0.002915007,0.0001731029,0.00006423757,0.0001650055,0.00236582,0.00005519435,0.00774655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00252451,"threshold_uncertainty_score":0.008445382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01390181584049405,"score_gpt":0.2192346846310253,"score_spread":0.2053328687905313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}