{"id":"W1979904436","doi":"10.1161/circulationaha.106.643585","title":"Tumor Necrosis Factor-α Mediates Cardiac Remodeling and Ventricular Dysfunction After Pressure Overload State","year":2007,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":378,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; University of Manitoba; Western University; Lawson Health Research Institute; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute for Health and Care Research","keywords":"Medicine; Pressure overload; Ventricular remodeling; Cardiology; Internal medicine; Tumor necrosis factor α; Tumor necrosis factor alpha; Heart failure; Cardiac hypertrophy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002117787,0.0004288308,0.0001930018,0.0001492489,0.0001175031,0.0002594826,0.0001547815,0.0001924644,0.000871984],"category_scores_gemma":[0.0002166393,0.0001001375,0.0001322011,0.00007455779,0.0003016769,0.0002246206,0.0001614754,0.0004373972,0.0002776588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001578689,"about_ca_system_score_gemma":0.0001007032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000969445,"about_ca_topic_score_gemma":0.00009232961,"domain_scores_codex":[0.9999204,0.00002345715,0.000006773297,0.00001082031,0.00001316138,0.00002544053],"domain_scores_gemma":[0.9998066,0.00002382579,0.0000793654,0.00001755179,0.00001740966,0.0000552412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003020906,0.0003080808,0.01407527,0.0001321889,0.00003205794,0.001534234,0.00007030254,0.0002038112,0.9733085,0.0002141937,0.000220186,0.006880372],"study_design_scores_gemma":[0.0006121752,0.005955822,0.2932802,0.0001052161,0.0002261862,0.009810302,0.0003581697,0.004278253,0.6798601,0.001531098,0.003958103,0.00002433796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948788,0.002572924,0.001362222,0.00009930775,0.00003499233,0.000015761,0.00006492012,0.00003526214,0.0009358582],"genre_scores_gemma":[0.9980819,0.0009940128,0.0002339127,0.00002302413,0.00003583874,0.00001215624,0.00009370318,0.000003329091,0.0005220422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000871984,"threshold_uncertainty_score":0.002917111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01060454468659707,"score_gpt":0.237085035911365,"score_spread":0.2264804912247679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}