{"id":"W1979996176","doi":"10.1126/scisignal.254pl1","title":"Genome to Kinome: Species-Specific Peptide Arrays for Kinome Analysis","year":2009,"lang":"en","type":"article","venue":"Science Signaling","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Saskatchewan","funders":"","keywords":"Kinome; Phosphorylation; Computational biology; Biology; Peptide; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004185643,0.0001628567,0.0002278083,0.0003127475,0.0005307064,0.000161816,0.0007865987,0.00004899281,0.0003628004],"category_scores_gemma":[0.00005151389,0.0001653159,0.0001724586,0.002091823,0.0001475044,0.0002542093,0.0000591968,0.0001250688,0.00002360323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002095266,"about_ca_system_score_gemma":0.00007099552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003264065,"about_ca_topic_score_gemma":7.609919e-7,"domain_scores_codex":[0.9981976,0.00000295635,0.0003017085,0.0006675916,0.0003095316,0.0005205726],"domain_scores_gemma":[0.9988595,0.00005302123,0.0001179633,0.0005846692,0.0001704412,0.000214402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007118031,0.00002158143,0.00009700556,0.000003789815,0.000008396527,6.009078e-7,0.0001000089,0.005496923,0.9841717,0.009316706,0.00001746439,0.0007586427],"study_design_scores_gemma":[0.0001198711,0.00004214445,0.001079409,0.00001413015,0.00004704125,0.00000182118,0.0001703481,0.0008189944,0.9452291,0.0121382,0.03996518,0.0003737737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3311819,0.00007220029,0.6607703,0.0006734222,0.00002164409,0.0003028277,0.00005203802,0.0001852298,0.006740451],"genre_scores_gemma":[0.7907649,0.00001103804,0.2078332,0.0002218375,0.0001881008,0.00008720596,0.00001882371,0.0000102362,0.000864696],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.459583,"threshold_uncertainty_score":0.6741387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02617490119145921,"score_gpt":0.2926249459104717,"score_spread":0.2664500447190125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}