{"id":"W1980087436","doi":"10.1254/jphs.fp0072181","title":"Systemic Glucocorticoid Therapy Reduces Pain and the Number of Endoneurial Tumor Necrosis Factor-Alpha (TNFα)-Positive Mast Cells in Rats With a Painful Peripheral Neuropathy","year":2008,"lang":"en","type":"article","venue":"Journal of Pharmacological Sciences","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Medicine; Triamcinolone acetonide; Neuropathic pain; Hyperalgesia; Sciatic nerve; Tumor necrosis factor alpha; Peripheral neuropathy; Allodynia; Nerve injury; Mast cell; Anesthesia; Glucocorticoid; Peripheral nerve injury; Internal medicine; Endocrinology; Immunology; Nociception; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000136233,0.0007680938,0.0007029149,0.000466443,0.0001555102,0.0002973852,0.0002530282,0.0003716798,0.001370628],"category_scores_gemma":[0.0002400683,0.0001681692,0.0002756902,0.0002072956,0.0004709631,0.0002481676,0.0001433708,0.0009022824,0.0002841704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002861128,"about_ca_system_score_gemma":0.0003085133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008915501,"about_ca_topic_score_gemma":0.001732598,"domain_scores_codex":[0.9998268,0.00002408066,0.00001402166,0.00003047741,0.00005246764,0.00005212337],"domain_scores_gemma":[0.9996446,0.00002129848,0.0001433682,0.00003446209,0.00003090499,0.0001253699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002099363,0.0003898736,0.000641539,0.0001201423,0.00002974127,0.000124323,0.00003179588,0.0001151043,0.9884135,0.00004456997,0.0001452481,0.007844886],"study_design_scores_gemma":[0.0008473238,0.03211654,0.02831075,0.00007196176,0.0002605396,0.001105918,0.0002294665,0.001273182,0.9322053,0.0001497385,0.00338945,0.00003971529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956021,0.002620262,0.0008167946,0.000114613,0.00006135773,0.00002470947,0.0001198088,0.0001573123,0.0004829221],"genre_scores_gemma":[0.9940347,0.002506232,0.001165633,0.00009778967,0.00006175185,0.00006262019,0.0003083644,0.00001909365,0.001743781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001370628,"threshold_uncertainty_score":0.004585266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02812418771602037,"score_gpt":0.2958911116950077,"score_spread":0.2677669239789873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}