{"id":"W1980105689","doi":"10.1016/s0264-410x(00)00362-5","title":"Expression and testing of Pseudomonas aeruginosa vaccine candidate proteins prepared with the Caulobacter crescentus S-layer protein expression system","year":2001,"lang":"en","type":"article","venue":"Vaccine","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of British Columbia","funders":"","keywords":"Caulobacter crescentus; Pilus; Pseudomonas aeruginosa; Microbiology; Epitope; Recombinant DNA; Fusion protein; Biology; Antibody; Titer; Chemistry; Bacteria; Biochemistry; Bacterial protein; Gene; Escherichia coli; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000771435,0.0007773605,0.0004199895,0.0003260626,0.0004284183,0.0004049856,0.0003399782,0.0006163944,0.0006540991],"category_scores_gemma":[0.0008270106,0.0002875331,0.0004953473,0.0004146662,0.0003967281,0.0005132271,0.0002432067,0.0009085992,0.000371582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008371179,"about_ca_system_score_gemma":0.0005906544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002547636,"about_ca_topic_score_gemma":0.002897691,"domain_scores_codex":[0.9994573,0.0001265704,0.00004678887,0.00007016028,0.0001810183,0.0001181317],"domain_scores_gemma":[0.9996035,0.0001258438,0.00006659867,0.00004870181,0.0001023855,0.00005308782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007286217,0.00008367857,0.0001073475,0.00002322908,0.000003290866,0.00002222224,0.00001693405,0.0001945964,0.9991757,0.00005795217,0.00001478695,0.000227205],"study_design_scores_gemma":[0.00001265671,0.0003436339,0.0004864801,0.000002197364,0.00001074647,0.00004789788,0.00002155355,0.0005781162,0.9981111,0.00001953508,0.0003635023,0.000002554988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936641,0.0002536084,0.005018426,0.0001209009,0.00002290832,0.0001177185,0.0003388523,0.00005176279,0.0004117633],"genre_scores_gemma":[0.9879658,0.0003626919,0.00840683,0.00006850816,0.000008862365,0.0001124994,0.001266728,0.00004457724,0.001763564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002547636,"threshold_uncertainty_score":0.006073713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007529727907112326,"score_gpt":0.2084906200768691,"score_spread":0.2009608921697568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}