{"id":"W1980124235","doi":"10.1182/blood-2009-07-230805","title":"Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; University of Oklahoma","keywords":"Arsenic trioxide; Acute promyelocytic leukemia; Medicine; Leukocytosis; Internal medicine; Chemotherapy; Neutropenia; Complete remission; Surgery; Gastroenterology; Arsenic","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006845466,0.0001774009,0.00018614,0.00003286997,0.00003565684,0.00001796104,0.0002212727,0.00009751089,0.000003124697],"category_scores_gemma":[0.00001516604,0.0001086403,0.00008264871,0.0001396536,0.00006091415,0.000003158667,0.00001030939,0.00005457972,0.000002066691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004317073,"about_ca_system_score_gemma":0.0001873705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000229037,"about_ca_topic_score_gemma":0.00002561431,"domain_scores_codex":[0.9991034,0.00005400566,0.0002017121,0.0002772782,0.0001442781,0.000219319],"domain_scores_gemma":[0.9994416,0.00001330349,0.00009397249,0.0003843563,0.00002951147,0.0000372876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002881112,0.003256181,0.02256921,0.00001958936,0.0004497571,0.0001414154,0.0007962428,0.0001556039,0.9532278,0.00003884381,0.0001267615,0.01893046],"study_design_scores_gemma":[0.005670785,0.005044541,0.01928297,0.0000235478,0.0002510747,0.0001423928,0.00007465611,0.000004813229,0.9680843,0.00003754264,0.001198767,0.0001846534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968051,0.001990166,0.00007020024,0.00006598428,0.00001460336,0.0004194934,0.000006467311,0.000008352413,0.0006196049],"genre_scores_gemma":[0.9980665,0.000906308,0.0005428402,0.0001123008,0.0001025663,0.00004119091,0.00007236914,0.00001282347,0.0001431403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01874581,"threshold_uncertainty_score":0.4430224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00771807102475839,"score_gpt":0.2202003492391789,"score_spread":0.2124822782144205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}