{"id":"W1980124235","doi":"10.1182/blood-2009-07-230805","title":"Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; University of Oklahoma","keywords":"Arsenic trioxide; Acute promyelocytic leukemia; Medicine; Leukocytosis; Internal medicine; Chemotherapy; Neutropenia; Complete remission; Surgery; Gastroenterology; Arsenic","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002539408,0.0001589352,0.0004951665,0.0001781131,0.0001679543,0.0001554465,0.0001817122,0.0001655511,0.0003075442],"category_scores_gemma":[0.000604076,0.0000735529,0.0002352493,0.0002343207,0.0002003158,0.0001586178,0.0001443351,0.0003228394,0.00008454667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002458205,"about_ca_system_score_gemma":0.0004061238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000484151,"about_ca_topic_score_gemma":0.001325103,"domain_scores_codex":[0.9998466,0.00006341098,0.00001768959,0.00002243303,0.00003287883,0.00001706781],"domain_scores_gemma":[0.9996636,0.00009257763,0.0001583091,0.00001430725,0.00002000912,0.00005123125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.02293311,0.001670212,0.2125316,0.001688619,0.0006715715,0.003044033,0.0006718953,0.003100817,0.1039326,0.0004476018,0.001585717,0.6477223],"study_design_scores_gemma":[0.006515179,0.1367601,0.6364577,0.0003631183,0.00205776,0.03250781,0.0009586639,0.002927806,0.1358246,0.0005892769,0.04497998,0.00005794813],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777118,0.02109391,0.0004854382,0.0001291759,0.00002046576,0.00002640253,0.00007106664,0.00002332507,0.0004383609],"genre_scores_gemma":[0.9919207,0.006454132,0.001228555,0.00005955057,0.00002961428,0.00003427822,0.0001103324,0.000004724963,0.0001580786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004951665,"threshold_uncertainty_score":0.001783609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00771807102475839,"score_gpt":0.2202003492391789,"score_spread":0.2124822782144205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}