{"id":"W1980157378","doi":"10.1159/000136433","title":"The in vivo Antibradykinin Activity of Seclazone (7-Chloro-3,3a-Dihydro-2H,9H-Isoxazolo[3,2-b] [1,3]Benzoxazin-9-One), a New Anti-Inflammatory Agent","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Bradykinin; Histamine; In vivo; Chemistry; Pharmacology; Guinea pig; Intradermal injection; Vascular permeability; Diuretic; Endocrinology; Medicine; Biochemistry; Immunology; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001598537,0.0004162849,0.0002785255,0.000161089,0.0001052306,0.0001464032,0.000169729,0.0002280074,0.001355078],"category_scores_gemma":[0.000148578,0.0001374036,0.0002138386,0.0001153525,0.0002581147,0.0001864886,0.00008159656,0.0007956465,0.000325331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001713075,"about_ca_system_score_gemma":0.0002495269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003674808,"about_ca_topic_score_gemma":0.0005881618,"domain_scores_codex":[0.9999087,0.00002156469,0.000006875623,0.00001417824,0.00001716466,0.00003144966],"domain_scores_gemma":[0.9998823,0.00002099708,0.00003440106,0.00001448705,0.00001266218,0.00003513801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007045161,0.000104168,0.0001666301,0.00004574329,0.00000639166,0.00003561115,0.000009316366,0.00004799551,0.9970514,0.00004758369,0.00003781468,0.001742958],"study_design_scores_gemma":[0.00009023037,0.00312296,0.004986149,0.000006168926,0.00002034318,0.0002121568,0.000009905791,0.0002786114,0.9903474,0.00002091946,0.0009026183,0.000002608463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929877,0.003445719,0.001620643,0.0001160336,0.00004811056,0.00002829113,0.0002526095,0.00006585177,0.001435127],"genre_scores_gemma":[0.9956873,0.001567249,0.0008904465,0.00002332891,0.00002329587,0.00002194807,0.0003900565,0.000008035205,0.001388399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001355078,"threshold_uncertainty_score":0.004533172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02230145222671534,"score_gpt":0.2551595657187635,"score_spread":0.2328581134920482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}