{"id":"W1980276110","doi":"10.1186/1471-2202-15-18","title":"Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes","year":2014,"lang":"en","type":"article","venue":"BMC Neuroscience","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Fondation pour la Recherche sur Alzheimer","keywords":"Purinergic receptor; Neuroscience; Purinergic signalling; Calcium signaling; Signal transduction; Calcium; Cell biology; Biology; Chemistry; Extracellular; Receptor; Biochemistry; Adenosine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001939262,0.0002105501,0.0002746966,0.0001350454,0.0001308798,0.0002477194,0.0001631111,0.0002346948,0.001260004],"category_scores_gemma":[0.0001524648,0.00008213514,0.000208511,0.0002604279,0.000111769,0.0001582716,0.0001497491,0.0004190111,0.0004327152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001336132,"about_ca_system_score_gemma":0.0001599697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006547677,"about_ca_topic_score_gemma":0.001076207,"domain_scores_codex":[0.9997672,0.00003010038,0.00004407871,0.00004452232,0.00008272321,0.00003137697],"domain_scores_gemma":[0.9998808,0.00002615842,0.00002227551,0.00001455676,0.00003919239,0.00001702379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001852708,0.00003415119,0.0002985504,0.00009751173,0.000006015707,0.0002876182,0.00005587961,0.00005343446,0.9966285,0.00002917823,0.00005599355,0.002267915],"study_design_scores_gemma":[0.00003610284,0.0007195329,0.01276903,0.00002043703,0.00003400392,0.0009272249,0.0001048321,0.0008964515,0.9795742,0.0000791915,0.004830955,0.000008034425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820675,0.006104623,0.006410745,0.0001778046,0.00007842031,0.0001254291,0.001291961,0.0001035604,0.003639983],"genre_scores_gemma":[0.988296,0.002627248,0.00548554,0.0001287953,0.00004405498,0.0002630167,0.0009552851,0.00001374577,0.002186416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001260004,"threshold_uncertainty_score":0.004215181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0327848604120133,"score_gpt":0.278971220331999,"score_spread":0.2461863599199857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}