{"id":"W1980294911","doi":"10.1038/sj.leu.2402486","title":"Bcr-abl-positive cells secrete angiogenic factors including matrix metalloproteinases and stimulate angiogenesis in vivo in Matrigel implants","year":2002,"lang":"en","type":"article","venue":"Leukemia","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"National Heart, Lung, and Blood Institute","keywords":"Matrigel; Angiogenesis; Chronic myelogenous leukemia; Hepatocyte growth factor; Matrix metalloproteinase; Cancer research; CD34; Biology; Bone marrow; Neovascularization; Immunology; Stem cell; Leukemia; Cell biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002079398,0.000508462,0.0008398463,0.0006583725,0.00009871631,0.0000401666,0.000155763,0.0002980848,0.000600771],"category_scores_gemma":[0.00006728836,0.000462735,0.0002106436,0.0007323138,0.00008621508,0.0002282467,0.0001757167,0.0002944797,0.00008454371],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003892784,"about_ca_system_score_gemma":0.0002082143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003671704,"about_ca_topic_score_gemma":0.0004031004,"domain_scores_codex":[0.9973483,0.000108601,0.0006180257,0.0007259113,0.0003949042,0.0008042214],"domain_scores_gemma":[0.9988443,0.0002326571,0.00016621,0.000437674,0.00004102979,0.0002781264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009055261,0.0004793347,0.4656941,0.0006900277,0.001135464,0.00727878,0.005934371,0.001935465,0.5080435,0.00006148649,0.001101553,0.006740388],"study_design_scores_gemma":[0.02639928,0.0009359039,0.3320363,0.001568019,0.001036431,0.0008630218,0.0008790936,0.02881503,0.604238,0.0001869818,0.001249264,0.001792706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933847,0.004398389,0.00001304386,0.0000550544,0.0001053488,0.001099926,0.0001561923,0.00009286717,0.0006945329],"genre_scores_gemma":[0.9966998,0.0006784271,0.0009056353,0.00009502294,0.00007009905,0.00005414194,0.00004938713,0.00007939242,0.001368146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1336578,"threshold_uncertainty_score":0.9999311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02715501353576848,"score_gpt":0.2727369351278328,"score_spread":0.2455819215920643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}