{"id":"W1980296375","doi":"10.1182/blood-2011-01-329656","title":"A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Labex Immuno-Oncology; Institut National Du Cancer; Université Pierre et Marie Curie; Université Paris Descartes; Ligue Contre le Cancer; Agence Nationale de la Recherche; Association pour la Recherche sur le Cancer","keywords":"CCR4; Immunology; Antigen; FOXP3; Population; CD8; Cytotoxic T cell; CCL17; Immune tolerance; Cancer research; Biology; Immune system; Medicine; Chemokine; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001555527,0.0004218425,0.0004907168,0.0002173895,0.0001002283,0.0002484335,0.0002392391,0.0002842146,0.001319104],"category_scores_gemma":[0.0001493131,0.0001506435,0.0002188854,0.0001021011,0.0001320298,0.0001671662,0.0001740936,0.0006140832,0.0004513765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001967825,"about_ca_system_score_gemma":0.0002924828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002443586,"about_ca_topic_score_gemma":0.00061897,"domain_scores_codex":[0.9997979,0.00004916943,0.000009296224,0.00002551643,0.00004051601,0.00007763032],"domain_scores_gemma":[0.9999293,0.00001454041,0.000019422,0.00000848329,0.00000741098,0.00002079516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002258014,0.0001569478,0.000116099,0.00003793401,0.00001261268,0.00002484755,0.000005756282,0.0001941156,0.9942273,0.00008366453,0.00008629744,0.004828653],"study_design_scores_gemma":[0.0001124675,0.00363284,0.0009442969,0.000006993851,0.00005214401,0.000169839,0.000008127949,0.001448865,0.9906886,0.00005146103,0.002879316,0.000005107685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897341,0.002941645,0.004316792,0.0001538445,0.00008216975,0.00009367646,0.0001112817,0.0001499959,0.002416587],"genre_scores_gemma":[0.9909762,0.001208363,0.0045069,0.0001359885,0.00006982234,0.00008626581,0.0002663082,0.00002874859,0.002721385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001319104,"threshold_uncertainty_score":0.004412889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0145206428073635,"score_gpt":0.193934427001518,"score_spread":0.1794137841941545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}