{"id":"W1980417454","doi":"10.1007/s00412-011-0356-3","title":"Mutability and mutational spectrum of chromosome transmission fidelity genes","year":2011,"lang":"en","type":"article","venue":"Chromosoma","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Terry Fox Foundation; National Cancer Institute; National Institutes of Health; Michael Smith Health Research BC; Princeton University","keywords":"Biology; Genetics; Gene; Mutant; Genetic screen; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001034818,0.0001304825,0.0001510683,0.00002209592,0.00005413748,0.000006346575,0.0001274712,0.0001164018,0.000156749],"category_scores_gemma":[0.0000158477,0.0001243801,0.00007170021,0.00004816216,0.0001574293,0.000004073772,0.0000658958,0.00004812538,0.000002770347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001009706,"about_ca_system_score_gemma":0.0000662521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004736131,"about_ca_topic_score_gemma":0.00001907856,"domain_scores_codex":[0.999179,0.00003168073,0.0002520654,0.0002911751,0.00009087867,0.000155188],"domain_scores_gemma":[0.9995043,0.000006174829,0.00009225841,0.000264148,0.00005033611,0.00008277955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005905855,0.0001553338,0.007313414,0.0001020128,0.00004462148,0.000005414126,0.0002761702,0.00001322876,0.9836776,0.0003347798,0.00003024751,0.007988099],"study_design_scores_gemma":[0.0005979513,0.000375208,0.1936093,0.00001715386,0.00002554556,0.00009168044,0.00007014522,0.0007518365,0.7998121,0.003431151,0.0009789669,0.0002389424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965385,0.0008277701,0.001415592,0.00003225216,0.00006028593,0.0001250107,0.0000497463,0.000008947655,0.0009419312],"genre_scores_gemma":[0.9958955,0.0001711371,0.003681083,0.00002812471,0.00006541259,0.000007462748,0.00008675262,0.00001513944,0.00004936381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1862959,"threshold_uncertainty_score":0.5072071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01152781231388512,"score_gpt":0.2159768436008364,"score_spread":0.2044490312869513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}