{"id":"W1980423403","doi":"10.1016/j.cellsig.2010.06.001","title":"Receptor tyrosine phosphatase sigma (RPTPσ) regulates, p250GAP, a novel substrate that attenuates Rac signaling","year":2010,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Phosphorylation; Cell biology; Tyrosine phosphorylation; Protein tyrosine phosphatase; Biology; FYN; GTPase; Phosphatase; Mutant; Signal transduction; Tyrosine kinase; Actin cytoskeleton; CDC42; Proto-oncogene tyrosine-protein kinase Src; Biochemistry; Cytoskeleton; Gene; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002033139,0.0003881536,0.0001746128,0.000191212,0.0002359261,0.0006099554,0.0003848321,0.0004138839,0.001128762],"category_scores_gemma":[0.0002572781,0.0001953401,0.0002074295,0.0001114887,0.0003479414,0.0002310004,0.0002636683,0.0008214121,0.0003629985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00039902,"about_ca_system_score_gemma":0.0002711016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005051089,"about_ca_topic_score_gemma":0.0007009893,"domain_scores_codex":[0.9997911,0.00003022571,0.00001094694,0.00004336303,0.00007004604,0.0000542569],"domain_scores_gemma":[0.9998602,0.00001807461,0.00004194074,0.00001837978,0.00001634027,0.00004502812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001038275,0.000009330766,0.0001139598,0.000007741308,0.000002917698,0.00007809643,0.000005557507,0.00001926849,0.9986477,0.0002098265,0.00006304509,0.000738599],"study_design_scores_gemma":[0.00002008255,0.00009736347,0.002589128,0.000003360012,0.00001423311,0.0006030002,0.0000309946,0.0007440791,0.9942349,0.0001122876,0.001547591,0.000003117982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924149,0.001252649,0.003713137,0.0003918911,0.00008750932,0.00001172684,0.0001428587,0.0001531232,0.001832181],"genre_scores_gemma":[0.9967372,0.0004293019,0.0009031563,0.00007728358,0.00001201364,0.00001140012,0.0001221088,0.00002941004,0.001678111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001128762,"threshold_uncertainty_score":0.003776073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01492028347249414,"score_gpt":0.2231953698210692,"score_spread":0.2082750863485751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}